ArticleMedicine2019
Outcomes of unplanned extubation in ordinary ward are similar to those in intensive care unit: A STROBE-compliant case-control study.
Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Factors for Post-operative Planned Reintubation in Patients After General Anesthesia: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Long-term impact of a quality improvement program on unplanned extubation and clinical outcomes in adult intensive care units: a 24-year single-center observational study.Frontiers in medicine · 2026Article
- A Risk Stratification Model for Unplanned Extubation a Chinese Tertiary Hospital Respiratory Intensive Care Unit: A Retrospective Study Based on Nursing-Related and Ventilation Characteristics.Risk management and healthcare policy · 2026Article
- Risk Prediction of Unplanned Extubation in Inpatients Using Random Forest and Logistic Regression Models.Journal of patient safety · 2025Article
- Parental presence in the pediatric intensive care unit reduces postoperative sedative requirements: A retrospective study.World journal of clinical pediatrics · 2025Article
- Prediction model for unplanned extubation of thoracoabdominal drainage tube in postoperative inpatients: a retrospective study.European journal of medical research · 2025Article
- Article
- Risk factors for unplanned reintubation caused by acute airway compromise after general anesthesia: a case-control study.BMC anesthesiology · 2021Article
- Real-Time Optical Monitoring of Endotracheal Tube Displacement.Biosensors · 2020Article
- Impact of performance improvement strategies on unplanned extubation in an inner-city intensive care unit.Therapeutic advances in respiratory diseaseObservational
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Unplanned extubation (UE) may cause considerable adverse effects in patients receiving mechanical ventilation (MV). Previous literature showed inconsistent prognosis in patients with UE. This study aimed to evaluate the clinical implications and outcomes of UE.The intubated adult patients with MV support in our hospital were enrolled, and they were divided into the UE and non-UE groups. Demographic data, admission unit, MV duration, overall weaning rate, and mortality rates were compared. The outcomes of UE in ordinary ward and intensive care unit (ICU) were also assessed.Totally 9245 intubated adult patients were included. UE occurred in 303 (3.5%) patients, and the UE events were 0.27 times/100 MV days. Old age, nonoperation related MV cause, and admission out of the ICU were significant factors associated with UE events. UE patients showed a trend of better overall weaning rate (71.9% vs 66.7%, P = .054) than non-UE. However, the in-hospital mortality rate (25.7% vs 24.8%, P = .713) were similar between the UE and non-UE patients. The reintubation rate of UE patients was 44.1% (142/322). Successful UEs were associated with patients in weaning process (52.8% vs 38.7%, P = .012), and patients received non-invasive positive pressure ventilation (NIPPV) support after UE (19.4% vs 3.5%, P < .001). Patients with successful UE had significantly shorter MV days, higher overall weaning rate, and lower mortality than those with unsuccessful UE. Outcomes of UE in ordinary ward and in ICU had similar MV duration, reintubation rate, overall weaning rate, and in-hospital mortality rate.The overall weaning rate and in-hospital mortality rates of the UE and non-UE patients were similar. UE occurred in ordinary ward had similar outcomes to those in ICU. Patients receiving MV should be assessed daily for weaning indications to reduce delayed extubation, and therefore, may decrease UE occurrence. Once the UE happened, NIPPV support may reduce the reintubation rate.
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