ArticleMedicine2019
The value of 18F-FDG PET/CT in the diagnosis of different size of solitary pulmonary nodules.
Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05066776 (Liquid Biopsy in Combination With PET/CT Versus PET/CT Alone in Diagnosis of Small Lung Nodules), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Liquid Biopsy in Combination With PET/CT Versus PET/CT Alone in Diagnosis of Small Lung Nodules
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Diagnosis value ofBMC medical imaging · 2023Pooled it
- The role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography SUVMax in deciding on a computed tomography-guided lung biopsy in solid solitary pulmonary nodules.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Predicting malignant potential of solitary pulmonary nodules in patients with COVID-19 infection: a comprehensive analysis of CT imaging and tumor markers.BMC infectious diseases · 2024Article
- An 18F-FDG-PET/CT-based radiomics signature for estimating malignance probability of solitary pulmonary nodule.The clinical respiratory journal · 2024Article
- Lung CT stabilization with high-frequency non-invasive ventilation (HF-NIV) and breath-hold (BH) in lung nodule assessment by PET/CT.European journal of hybrid imaging · 2023Article
- Staging Prostate Cancer withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Article
- Combined measurement of circulating tumor cell counts and serum tumor marker levels enhances the screening efficiency for malignant versus benign pulmonary nodules.Thoracic cancer · 2022Article
- Differentiation Between Malignant and Benign Pulmonary Nodules by Using Automated Three-Dimensional High-Resolution Representation Learning With Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography.Frontiers in medicine · 2022Article
- Managing of screening-detected sub-solid nodules-a European perspective.Translational lung cancer research · 2021Review
- A narrative review of invasive diagnostics and treatment of early lung cancer.Translational lung cancer research · 2021Review
- Flip flop fungus sign: an FDG PET sign of benign pulmonary nodules.BMJ case reports · 2020Article
- Value of Shape and Texture Features fromDiagnostics (Basel, Switzerland) · 2020Article
- [Value of preoperative localization techniques for solitary pulmonary nodules in singleport thoracoscopic surgery].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate the diagnostic value of F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) for solitary pulmonary nodules (SPNs) with different diameters.One hundred eighty two consecutive patients with SPN who underwent F-FDG PET/CT examination were retrospectively studied. Patients were categorized into 3 groups according to the diameter of nodules: Group A with the diameter of greater than or equal to 6 mm and less than or equal to 10 mm; Group B with diameter greater than 10 mm and less than or equal to 20 mm; Group C with diameter greater than 20 mm and less than or equal to 30 mm. The efficiency of PET/CT, PET and CT in the diagnosis of benign and malignant SPNs and different subgroup of SPNs was calculated. Receiver operating characteristic curves (ROCs) were drawn and area under the curves (AUCs) were compared between different groups.The age, diameter, mean standardized uptake value (SUVmean) and maximum standardized uptake value (SUVmax) of benign and malignant nodules were significantly different (P < .05). For overall SPNs, the sensitivity, specificity, accuracy, PPV, and NPV of PET/CT were 98.35%, 77.05%, 91.21%, 89.47%, and 95.92%, respectively. The AUC of PET/CT was significantly larger than that of SUVmean, SUVmax, and CT (P < .05). For different size of SPNs, the AUC of PET/CT in group A was higher than that in group B and group C, but there was no significant difference with CT (P > .05). In group B, the accuracy of PET/CT in the diagnosis of SPN was significantly higher than that of CT (P < .05).F-FDG PET/CT demonstrated excellent performance in identifying different size of SPNs, especially for those with diameter between 11 and 20 mm, the diagnostic value of F-FDG PET/CT is significantly higher than other methods.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.