Evidence map›Paper›PMID 30882318›Full record

ArticleEmerging infectious diseases2019

Clinical Manifestations and Molecular Diagnosis of Scrub Typhus and Murine Typhus, Vietnam, 2015-2017.

Nguyen Vu Trung, Le Thi Hoi, Vu Minh Dien, Dang Thi Huong, Tran Mai Hoa, Vu Ngoc Lien, Phan Van Luan, Sonia Odette Lewycka, Marc Choisy, Juliet E Bryant and 4 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The temporal dynamics of humoral immunity to Rickettsia typhi infection in murine typhus patients.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
    Trial
  3. Review
  4. Article
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  7. Epidemiology of Murine Typhus in Taiwan from 2013 to 2020.The American journal of tropical medicine and hygiene · 2024
    Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nguyen Vu Trung
Le Thi Hoi
Vu Minh Dien
Dang Thi Huong
Tran Mai Hoa
Vu Ngoc Lien
Phan Van Luan
Sonia Odette Lewycka
Marc Choisy
Juliet E Bryant
Behzad Nadjm
H Rogier van Doorn
Allen L Richards
Nguyen Van Kinh

Funding

Wellcome Trust
6 · The paper itself

Abstract

Rickettsioses are endemic to Vietnam; however, only a limited number of clinical studies have been performed on these vectorborne bacteria. We conducted a prospective hospital-based study at 2 national referral hospitals in Hanoi to describe the clinical characteristics of scrub typhus and murine typhus in northern Vietnam and to assess the diagnostic applicability of quantitative real-time PCR assays to diagnose rickettsial diseases. We enrolled 302 patients with acute undifferentiated fever and clinically suspected rickettsiosis during March 2015-March 2017. We used a standardized case report form to collect clinical information and laboratory results at the time of admission and during treatment. We confirmed scrub typhus in 103 (34.1%) patients and murine typhus in 12 (3.3%) patients. These results highlight the need for increased emphasis on training for healthcare providers for earlier recognition, prevention, and treatment of rickettsial diseases in Vietnam.

Indexed as

AdultEarly DiagnosisFemaleHumansMaleMiddle AgedPathology, MolecularProspective StudiesScrub TyphusSerotypingTyphus, Endemic Flea-BorneVietnambacteriaclinical manifestationsmolecular diagnosismurine typhusrickettsial diseasesScrub typhusVietnam

Identifiers

PMID30882318
PMCPMC6433017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.