Evidence map›Paper›PMID 30882316›Full record

ArticleEmerging infectious diseases2019

Co-infections in Persons with Early Lyme Disease, New York, USA.

Gary P Wormser, Donna McKenna, Carol Scavarda, Denise Cooper, Marc Y El Khoury, John Nowakowski, Praveen Sudhindra, Alexander Ladenheim, Guiqing Wang, Carol L Karmen and 3 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Global meta-analysis onPathogens and global health · 2022
    Pooled it
  2. Lyme Disease and Other Tick-Borne Infections.Current neurology and neuroscience reports · 2026
    Review
  3. Article
  4. The Lyme Disease Vaccine Paradox.Journal of clinical medicine · 2026
    Article
  5. Global prevalence ofNew microbes and new infections · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. The Surveillance ofVeterinary sciences · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gary P Wormser
Donna McKenna
Carol Scavarda
Denise Cooper
Marc Y El Khoury
John Nowakowski
Praveen Sudhindra
Alexander Ladenheim
Guiqing Wang
Carol L Karmen
Valerie Demarest
Alan P Dupuis
Susan J Wong

Funding

NCEZID CDC HHS R01 CK000152
6 · The paper itself

Abstract

In certain regions of New York state, USA, Ixodes scapularis ticks can potentially transmit 4 pathogens in addition to Borrelia burgdorferi: Anaplasma phagocytophilum, Babesia microti, Borrelia miyamotoi, and the deer tick virus subtype of Powassan virus. In a prospective study, we systematically evaluated 52 adult patients with erythema migrans, the most common clinical manifestation of B. burgdorferi infection (Lyme disease), who had not received treatment for Lyme disease. We used serologic testing to evaluate these patients for evidence of co-infection with any of the 4 other tickborne pathogens. Evidence of co-infection was found for B. microti only; 4-6 patients were co-infected with Babesia microti. Nearly 90% of the patients evaluated had no evidence of co-infection. Our finding of B. microti co-infection documents the increasing clinical relevance of this emerging infection.

Indexed as

Babesia microtiLyme DiseaseTick-Borne DiseasesBabesiosisCoinfectionHumansNew YorkProspective StudiesAnaplasmaBabesiabacteriaBorrelia burgdorferiBorrelia miyamotoico-infectionerythema migransLyme diseaseNew YorkparasitesPowassan virusUnited Statesviruses

Identifiers

PMID30882316
PMCPMC6433014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.