Evidence map›Paper›PMID 30882277›Full record

ArticleTissue engineering. Part A2019

Juliana A Passipieri, Xiao Hu, Ellen Mintz, Jack Dienes, Hannah B Baker, C Hunter Wallace, Silvia S Blemker, George J Christ

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  11. Review
  12. Tissue engineering. Part C, Methods · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Juliana A PassipieriDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.
Xiao HuDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.
Ellen MintzDepartment of Pathology, University of Virginia, Charlottesville, Virginia.
Jack DienesDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.
Hannah B BakerWake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, North Carolina.
C Hunter WallaceDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.
Silvia S BlemkerDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.
George J ChristDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.
University of Virginia · USForest Institute · US

Funding

Multiscale Modeling for Treatment Discovery in Duchenne Muscular DystrophyU01AR069393 · NIAMS · UNIVERSITY OF VIRGINIA · PI BLEMKER, SILVIA SALINAS, PEIRCE-COTTLER, SHAYN · 2016 to 2020
$2.5M
Studies in Translational Regenerative MedicineT32EB014836 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ANTHONY ATALA, Victoria Weis · 2013 to 2026
$1.7M
NIAMS NIH HHS U01 AR069393NIBIB NIH HHS T32 EB014836
6 · The paper itself

Abstract

impact statementDespite medical advances, volumetric muscle loss (VML) injuries to craniofacial muscles represent an unmet clinical need. We report an implantable tissue-engineered construct that leads to substantial tissue regeneration and functional recovery in a preclinical model of VML injury that is dimensionally relevant to unilateral cleft lip repair, and a series of corresponding computational models that provide biomechanical insight into mechanism(s) responsible for the VML-induced functional deficits and recovery following tissue-engineered muscle repair implantation. This unique combined approach represents a critical first step toward establishing a crucial biomechanical basis for the development of efficacious regenerative technologies, considering the spectrum of VML injuries.

Indexed as

AnimalsDisease Models, AnimalMaleMuscle, SkeletalMuscular DiseasesRatsRecovery of FunctionTissue EngineeringWound Healingcleft lipfinite-element modelfunctional recoveryrat latissimus dorsirevascularizationvolumetric muscle loss

Identifiers

PMID30882277
PMCPMC6760186
OpenAlexW2921468931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.