Evidence map›Paper›PMID 30882000›Full record

ReviewBioMed research international2019

Antioxidants as Renoprotective Agents for Ischemia during Partial Nephrectomy.

Gabriela F Buys-Gonçalves, Leonardo A S Abreu, Bianca M Gregorio, Francisco J B Sampaio, Marco A Pereira-Sampaio, Diogo B de Souza

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cytoprotective Action of Sodium Fumarate in anSovremennye tekhnologii v meditsine · 2025
    Article
  4. Impact of a kidney-adjusted ERASLangenbeck's archives of surgery · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The efficiency of oxerutin on apoptosis and kidney function in rats with renal ischemia reperfusion injury.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Quercetin as a nephroprotector after warm ischemia: histomorphometric evaluation in a rodent model.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Gabriela F Buys-GonçalvesUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.
Leonardo A S AbreuUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.
Bianca M GregorioUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-7284-0362
Francisco J B SampaioUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.
Marco A Pereira-SampaioUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.
Diogo B de SouzaUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.ORCID 0000-0003-3456-5029
Universidade do Estado do Rio de Janeiro · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small renal masses have been diagnosed increasingly in recent decades, allowing surgical treatment by partial nephrectomy. This treatment option is associated with better renal function preservation, in comparison with radical nephrectomy. However, for obtaining a bloodless field during surgery, occlusion of renal artery and veins is often required, which results in transitory ischemia. The renal ischemia-reperfusion injury is associated with increased reactive oxygen species production leading to renal tissue damage. Thus, the use of antioxidants has been advocated in the partial nephrectomy perioperative period. Several antioxidants were investigated in regard to renal ischemia-reperfusion injury. The present manuscript aims to present the literature on the most commonly studied antioxidants used during partial nephrectomy. The results of experimental and clinical studies using antioxidants during partial nephrectomy are reported. Further, alimentary sources of some antioxidants are presented, stimulating future studies focusing on perioperative antioxidant-rich diets.

Indexed as

AntioxidantsHumansKidneyKidney NeoplasmsNephrectomyPerioperative PeriodRenal ArteryReperfusion InjuryAntioxidants

Identifiers

PMID30882000
PMCPMC6383545
OpenAlexW2912546084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.