Evidence map›Paper›PMID 30881925›Full record

ArticleFrontiers in cellular and infection microbiology2019

Oral Vaccination With a Formulation Combining

Marinela Contreras, Paul D Kasaija, Octavio Merino, Ned I de la Cruz-Hernandez, Christian Gortazar, José de la Fuente

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Complement system activation in wild boar (Frontiers in veterinary science · 2025
    Article
  4. Evolution of tick vaccinology.Parasitology · 2024
    Review
  5. Review
  6. Will we ever eradicate animal tuberculosis?Irish veterinary journal · 2023
    Article
  7. Universal Tick Vaccines: Candidates and Remaining Challenges.Animals : an open access journal from MDPI · 2023
    Review
  8. Recent Advances in Tick Antigen Discovery and Anti-Tick Vaccine Development.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Effect of polyphenols extracted fromJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Marinela ContrerasSaBio, Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ciudad Real, Spain.
Paul D KasaijaSaBio, Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ciudad Real, Spain.
Octavio MerinoFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Tamaulipas, Ciudad Victoria, Mexico.
Ned I de la Cruz-HernandezFacultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Tamaulipas, Ciudad Victoria, Mexico.
Christian GortazarSaBio, Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ciudad Real, Spain.
José de la FuenteSaBio, Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ciudad Real, Spain.
Instituto de Investigación en Recursos Cinegéticos · ESAutonomous University of Tamaulipas · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines are an environmentally friendly alternative to acaracides for the control of tick infestations, to reduce the risk for tick-borne diseases affecting human and animal health worldwide, and to improve animal welfare and production. Subolesin (SUB, also known as 4D8) is the functional homolog of Akirin2 involved in the regulation of development and innate immune response, and a proven protective antigen for the control of ectoparasite infestations and pathogen infection. Oral vaccination combining protein antigens with immunostimulants has proven efficacy with increased host welfare and safety, but has not been used for the control of tick infestations. Here we describe the efficacy of oral vaccination with a formulation combining

Indexed as

Administration, OralAnimalsAntigensArthropod ProteinsCattleDisease Models, AnimalFertilityImmunologic FactorsIncidenceMycobacterium bovisRhipicephalusSurvival AnalysisTick InfestationsTreatment OutcomeVaccinationAntigensArthropod ProteinsImmunologic Factorssubolesin, tickcattle tickheat inactivated Mycobacterium bovisoral vaccinationRhipicephalus microplussubolesinvaccine

Identifiers

PMID30881925
PMCPMC6407321
OpenAlexW2918181493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.