Evidence map›Paper›PMID 30881871›Full record

ArticleCardiovascular diagnosis and therapy2019

Association between serum adropin level and coronary artery disease: a systematic review and meta-analysis.

Jiankang Zheng, Mao Liu, Ling Chen, Feng Yin, Xiao Zhu, Junqi Gou, Wei Zeng, Zhan Lv

Abstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Adropin's Role in Energy Homeostasis and Metabolic Disorders.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiankang ZhengDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong 637100, China.
Mao LiuDepartment of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China.
Ling ChenDepartment of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China.
Feng YinDepartment of Clinical Medicine, Xiangya School of Medicine, Central South University, Changsha 410083, China.
Xiao ZhuDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong 637100, China.
Junqi GouDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong 637100, China.
Wei ZengDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong 637100, China.
Zhan LvDepartment of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have found that adropin is associated with coronary artery disease (CAD). This meta-analysis sought to assess the relationship between serum adropin level and CAD.

methodsOnline databases including the Cochrane Library, PubMed, EMbase, Ovid, CBM, CNKI, VIP and WanFang Data were electronically searched for the clinical study concerning the relationship between serum adropin levels and CAD, including acute myocardial infarction (AMI), unstable angina pectoris (UAP), and stable angina pectoris (SAP). Two reviewers independently screened literature, extracted data and assessed methodological quality of included studies. Standard mean difference (SMD) with its 95% confidence interval (CI) was used as the effect size in this study. Then meta-analysis was performed using RevMan 5.2 software.

resultsA total of seven articles involved 945 participants were included. The results indicated that serum adropin level in CAD group was lower than healthy control group (SMD =-2.44, P=0.0008). In the subgroup analysis, the levels of serum adropin in AMI group (SMD =-2.96, P<0.00001), UAP group (SMD =-2.09, P=0.0001) and SAP group (SMD =-1.23, P=0.007) were also lower than that of healthy control.

conclusionsSerum adropin level in patients with CAD was lower than healthy individuals, indicating that the decrease of adropin concentration might play an important role in the development of CAD.

Indexed as

Adropincoronary artery disease (CAD)meta-analysis

Identifiers

PMID30881871
PMCPMC6382666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.