Evidence map›Paper›PMID 30881662›Full record

ArticleChemical science2019

Simultaneous dual-colour tracking lipid droplets and lysosomes dynamics using a fluorescent probe.

Xujun Zheng, Wencheng Zhu, Fan Ni, Hua Ai, Shaolong Gong, Xiang Zhou, Jonathan L Sessler, Chuluo Yang

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  16. Lipid droplet motility and organelle contacts.Contact (Thousand Oaks (Ventura County, Calif.))
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xujun ZhengDepartment of Chemistry , Hubei Key Lab on Organic and Polymeric Optoelectronic Materials , Wuhan University , Wuhan 430072 , P. R. China . Email: clyang@whu.edu.cn.
Wencheng ZhuNational Engineering Research Center for Biomaterials , Sichuan University , Chengdu 610064 , P. R. China . Email: huaai@scu.edu.cn.
Fan NiDepartment of Chemistry , Hubei Key Lab on Organic and Polymeric Optoelectronic Materials , Wuhan University , Wuhan 430072 , P. R. China . Email: clyang@whu.edu.cn.
Hua AiNational Engineering Research Center for Biomaterials , Sichuan University , Chengdu 610064 , P. R. China . Email: huaai@scu.edu.cn.
Shaolong GongDepartment of Chemistry , Hubei Key Lab on Organic and Polymeric Optoelectronic Materials , Wuhan University , Wuhan 430072 , P. R. China . Email: clyang@whu.edu.cn.ORCID 0000-0002-1166-9047
Xiang ZhouDepartment of Chemistry , Hubei Key Lab on Organic and Polymeric Optoelectronic Materials , Wuhan University , Wuhan 430072 , P. R. China . Email: clyang@whu.edu.cn.ORCID 0000-0002-1829-9368
Jonathan L SesslerCenter for Supramolecular Chemistry and Catalysis , Shanghai University , Shanghai 200444 , P. R. China.
Chuluo YangDepartment of Chemistry , Hubei Key Lab on Organic and Polymeric Optoelectronic Materials , Wuhan University , Wuhan 430072 , P. R. China . Email: clyang@whu.edu.cn.ORCID 0000-0001-9337-3460

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After entering a cell, most small molecule fluorescent probes are dispersed in the cytoplasm before they then accumulate in a specific organelle or subcellular zone. Molecules that can enter two or more organelles with high selectivity are all but unknown. In this work, we report a naphthalimide-based fluorescent probe,

Identifiers

PMID30881662
PMCPMC6385674

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.