Evidence map›Paper›PMID 30881586›Full record

ArticleOxidative medicine and cellular longevity2019

Peptides from Cauliflower By-Products, Obtained by an Efficient, Ecosustainable, and Semi-Industrial Method, Exert Protective Effects on Endothelial Function.

C Caliceti, A L Capriotti, D Calabria, F Bonvicini, R Zenezini Chiozzi, C M Montone, S Piovesana, M Zangheri, M Mirasoli, P Simoni and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

C CalicetiDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum-University of Bologna, Bologna, Italy.ORCID 0000-0002-6740-5331
A L CapriottiDepartment of Chemistry, Università di Roma "La Sapienza", Rome, Italy.
D CalabriaDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum-University of Bologna, Bologna, Italy.
F BonviciniDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Bologna, Italy.
R Zenezini ChiozziDepartment of Chemistry, Università di Roma "La Sapienza", Rome, Italy.
C M MontoneDepartment of Chemistry, Università di Roma "La Sapienza", Rome, Italy.
S PiovesanaDepartment of Chemistry, Università di Roma "La Sapienza", Rome, Italy.
M ZangheriDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum-University of Bologna, Bologna, Italy.
M MirasoliDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum-University of Bologna, Bologna, Italy.
P SimoniDepartment of Medical and Surgical Sciences, Alma Mater Studiorum-University of Bologna, Bologna, Italy.
A LaganàDepartment of Chemistry, Università di Roma "La Sapienza", Rome, Italy.
A RodaDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum-University of Bologna, Bologna, Italy.ORCID 0000-0001-7649-4797
University of Bologna · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The large amount of cauliflower industry waste represents an unexplored source of bioactive compounds. In this work, peptide hydrolysates from cauliflower leaves were characterized by combined bioanalytical approaches. Twelve peptide fractions were studied to evaluate unexplored biological activities by effect-based cellular bioassays. A potent inhibition of intracellular xanthine oxidase activity was observed in human vascular endothelial cells treated with one fraction, with an IC50 = 8.3 ± 0.6

Indexed as

BrassicaEndothelial CellsHumansPeptidesXanthine OxidasePeptidesXanthine Oxidase

Identifiers

PMID30881586
PMCPMC6381550
OpenAlexW2911269783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.