Evidence map›Paper›PMID 30881585›Full record

ArticleCurrent cardiovascular imaging reports2016

Intravascular NIRF Molecular Imaging Approaches in Coronary Artery Disease.

Tetsuya Hara, Farouc A Jaffer

Open access · greenAbstract read
In one paragraph

Article in Current cardiovascular imaging reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Imaging Approaches to the Diagnosis of Vascular Diseases.Current atherosclerosis reports · 2022
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Tetsuya HaraDivision of Cardiovascular Medicine, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki cho, chuo ku, Kobe, Hyogo, Japan, Tel. (078) 382-5846, Fax. (078) 382-5849.
Farouc A JafferCardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, 185 Cambridge St, Boston, MA, USA., Tel. (617) 724-9353, Fax. (617) 860-3180.
Kobe University · JPMassachusetts General Hospital · US

Funding

NIRF-OFDI of Inflammation in Atheroma Progression and Stent ComplicationsR01HL122388 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI JAFFER, FAROUC AMIN · 2015 to 2018
$2.1M
NHLBI NIH HHS R01 HL122388
6 · The paper itself

Abstract

Progression of vulnerable coronary atherosclerotic plaques underlies the majority of acute myocardial infarction and sudden cardiac death episodes. Recent advances in biological/molecular imaging technology are now enabling the accurate identification of high-risk plaques and stents in living subjects. Due to their smaller caliber and susceptibility to cardiorespiratory motion, noninvasive molecular imaging of human coronary arteries remains challenging. Therefore, intravascular high-resolution molecular imaging approaches appear necessary to resolve molecular features of human coronary arteries and stents. Here we present recent progress in intravascular near-infrared fluorescence (NIRF) molecular imaging, including the evolution from standalone NIRF systems to those integrated with structural imaging methods including optical coherence tomography and intravascular ultrasound. Preclinical demonstrations of imaging inflammation, fibrin, and endothelial impairment are highlighted. We then close with a discussion of translation of NIRF imaging to the cardiac catheterization laboratory and showcase first-in-human intracoronary imaging results of NIR autofluorescence in CAD.

Indexed as

coronary artery disease (CAD)inflammationintravascular imagingintravascular near-infrared fluorescence (NIRF)

Identifiers

PMID30881585
PMCPMC6419760
OpenAlexW2302014574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.