Evidence map›Paper›PMID 30881503›Full record

ArticleOncology letters2019

p53 overexpression is a prognosticator of poor outcome in esophageal cancer.

Nathaniel Melling, Sonja Norrenbrock, Martina Kluth, Ronald Simon, Claudia Hube-Magg, Stefan Steurer, Andrea Hinsch, Eike Burandt, Frank Jacobsen, Waldemar Wilczak and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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  15. Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Nathaniel MellingDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Sonja NorrenbrockInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Martina KluthInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Ronald SimonInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Claudia Hube-MaggInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Stefan SteurerInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Andrea HinschInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Eike BurandtInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Frank JacobsenInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Waldemar WilczakInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Alexander QuaasInstitute for Pathology, University Hospital Cologne, D-50937 Cologne, Germany.
Maximillian BockhornDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Katharina GruppDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Michael TachezyDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Jakob IzbickiDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Guido SauterInstitute for Pathology, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Florian GebauerDepartment of Surgery, University Hospital Cologne, D-50937 Cologne, Germany.
Universität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DEUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunohistochemistry studies on p53 inactivation in esophageal cancer are available with inconclusive results. Data on the combined effect of p53 protein accumulation and

Indexed as

esophageal canceroutcomep53 expression

Identifiers

PMID30881503
PMCPMC6403495
OpenAlexW2914102443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.