ArticleNature physics2018
Entropic effects in cell lineage tree packings.
Article in Nature physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- Tetrahedron clusters serving as a platform for foam-like structure design.Nanoscale advances · 2024Article
- Fusome topology and inheritance during insect gametogenesis.PLoS computational biology · 2023Article
- Mechanics of stabilized intercellular bridges.Biophysical journal · 2022Article
- Quantitative models for building and growing fated small cell networks.Interface focus · 2022Review
- Varied solutions to multicellularity: The biophysical and evolutionary consequences of diverse intercellular bonds.Biophysics reviews · 2022Review
- Cellular organization in lab-evolved and extant multicellular species obeys a maximum entropy law.eLife · 2022Article
- Clonal dominance in excitable cell networks.Nature physics · 2021Article
- Size scaling in collective cell growth.Development (Cambridge, England) · 2021Article
- Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Dynamics of hydraulic and contractile wave-mediated fluid transport duringProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Tissue topography steers migratingScience (New York, N.Y.) · 2020Article
- How geometry shapes division of labor.eLife · 2020Article
- Testing Models of mRNA Localization Reveals Robustness Regulated by Reducing Transport between Cells.Biophysical journal · 2019Article
- Embryonic Inversion inPhysical review. E · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Optimal packings [1, 2] of unconnected objects have been studied for centuries [3-6], but the packing principles of linked objects, such as topologically complex polymers [7, 8] or cell lineages [9, 10], are yet to be fully explored. Here, we identify and investigate a generic class of geometrically frustrated tree packing problems, arising during the initial stages of animal development when interconnected cells assemble within a convex enclosure [10]. Using a combination of 3D imaging, computational image analysis, and mathematical modelling, we study the tree packing problem in Drosophila egg chambers, where 16 germline cells are linked by cytoplasmic bridges to form a branched tree. Our imaging data reveal non-uniformly distributed tree packings, in agreement with predictions from energy-based computations. This departure from uniformity is entropic and affects cell organization during the first stages of the animal's development. Considering mathematical models of increasing complexity, we investigate spherically confined tree packing problems on convex polyhedrons [11] that generalize Platonic and Archimedean solids. Our experimental and theoretical results provide a basis for understanding the principles that govern positional ordering in linked multicellular structures, with implications for tissue organization and dynamics [12, 13].
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.