ArticleInternational journal of endocrinology and metabolism2019
Vitamin D Increases Glucose Stimulated Insulin Secretion from Insulin Producing Beta Cells (INS1E).
Article in International journal of endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Vitamin D Receptor Polymorphisms and the Effect of Vitamin D Supplementation on Diabetes Risk Among Adults With Prediabetes.JAMA network open · 2026Trial
- Trial
- Association of CYP2R1 gene polymorphisms with type 2 diabetes mellitus in the Jordanian population.Journal, genetic engineering & biotechnology · 2026Article
- Therapeutic potential of vitamin D in improving antioxidant defense and blood rheology in a rat model of experimental diabetes mellitus.Open medicine (Warsaw, Poland) · 2026Article
- Association of circulating 25-hydroxyvitamin D with time in range and insulin secretion in type 2 diabetes.Frontiers in endocrinology · 2025Article
- Relationship between vitamin D deficiency and gestational diabetes: a narrative review.Frontiers in endocrinology · 2024Review
- Beta Cell Dysfunction in Youth- and Adult-Onset Type 2 Diabetes: An Extensive Narrative Review with a Special Focus on the Role of Nutrients.Nutrients · 2023Review
- Vitamin D and Diabetic Kidney Disease.International journal of molecular sciences · 2023Review
- Transcriptional signature of islet neogenesis-associated protein peptide-treated rat pancreatic islets reveals induction of novel long non-coding RNAs.Frontiers in endocrinology · 2023Article
- The link between vitamin D, chemerin and metabolic profile in overweight and obese children - preliminary results.Frontiers in endocrinology · 2023Article
- Association of Serum 25(OH)D with Metabolic Syndrome in Chinese Women of Childbearing Age.Nutrients · 2022Article
- Vitamin D Deficiency Association with Comorbid Diseases in Palestine: "A Cross-Sectional Observation Study".International journal of general medicine · 2022Article
- Insulin-resistance and depression cohort data mining to identify nutraceutical related DNA methylation biomarker for type 2 diabetes.Genes & diseases · 2021Article
- Vitamin D and Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): An Update.Nutrients · 2020Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin D affects the pancreatic beta cell function and in vitro studies have shown that vitamin D may influence insulin secretion, apoptosis, and gene regulation. However, the outcomes have differed and there has been uncertainty regarding the effect of different vitamin D metabolites on insulin secretion.
objectivesWe hypothesized that vitamin D could increase insulin secretion in insulin producing beta cells and investigated the effect of 25(OH) vitamin D and 1,25(OH)
methodsThe study was conducted in INS1E cells, an established insulinoma cell line from rat. The cells were divided into three groups; a control group, a group with 1,25(OH)
resultsINS1E cells treated with 1,25(OH)
conclusionsTreatment with 1,25(OH)
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.