Evidence map›Paper›PMID 30881451›Full record

ArticleInternational journal of endocrinology2019

Study of the Potential Endocrine-Disrupting Effects of Phenylurea Compounds on Neurohypophysis Cells

Krisztián Sepp, Zsolt Molnár, Anna M László, Tünde Alapi, László Tóth, Andrea Serester, Zsuzsanna Valkusz, Márta Gálfi, Marianna Radács

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In one paragraph

Article in International journal of endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Krisztián SeppFirst Department of Internal Medicine, Faculty of Medicine, University of Szeged, Szeged, Hungary.ORCID 0000-0001-9400-5213
Zsolt MolnárInstitute of Applied Science, Department of Environmental Biology and Education, Gyula Juhász Faculty of Education, University of Szeged, Szeged, Hungary.
Anna M LászlóDepartment of Biometrics and Agricultural Informatics, Faculty of Horticultural Science, Szent István University, Budapest, Hungary.
Tünde AlapiDepartment of Inorganic and Analytical Chemistry, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
László TóthInstitute of Applied Science, Department of Environmental Biology and Education, Gyula Juhász Faculty of Education, University of Szeged, Szeged, Hungary.
Andrea SeresterInstitute of Applied Science, Department of Environmental Biology and Education, Gyula Juhász Faculty of Education, University of Szeged, Szeged, Hungary.
Zsuzsanna ValkuszFirst Department of Internal Medicine, Faculty of Medicine, University of Szeged, Szeged, Hungary.
Márta GálfiInstitute of Applied Science, Department of Environmental Biology and Education, Gyula Juhász Faculty of Education, University of Szeged, Szeged, Hungary.
Marianna RadácsInstitute of Applied Science, Department of Environmental Biology and Education, Gyula Juhász Faculty of Education, University of Szeged, Szeged, Hungary.
University of Szeged · HUMagyar Agrár- és Élettudományi Egyetem · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homeostatic disruptor agents, and endocrine disruptor compounds (EDC) specifically, can originate from agricultural and industrial chemicals. If they modify the adaptation of living organisms as direct (e.g., by altering hormone regulation, membrane functions) and/or indirect (e.g., cell transformation mechanisms) factors, they are classified as EDC. We aimed to examine the potential endocrine-disrupting effects of phenylurea herbicides (phenuron, monuron, and diuron) on the oxytocin (OT) and arginine-vasopressin (AVP) release of neurohypophysis cell cultures (NH). In our experiments, monoamine-activated receptor functions of neurohypophyseal cells were used as a model.

Identifiers

PMID30881451
PMCPMC6387713
OpenAlexW2914526554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.