ArticlePakistan journal of medical sciences
Ambiguous genitalia: An overview of 7 years experience at the Children's Hospital & Institute of Child Health, Lahore, Pakistan.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Ambiguous genitalia in a male patient misidentified as female, leading to inappropriate circumcision: A rare case report.Radiology case reports · 2025Article
- Prevalence of Differences of Sex Development Among Pediatric Endocrine Care Centers in Switzerland From 2000 to 2019.Journal of the Endocrine Society · 2025Article
- Categorization of differences of sex development among Egyptian children and the role of antimullerian hormone and inhibin B.Frontiers in endocrinology · 2022Article
- Ambiguous genitalia: clinical management of adult female with male assigned gender: a case report.Journal of medical case reports · 2021Article
- The Application Value of Magnetic Resonance Imaging (MRI) in the Clinical Diagnosis in Hospital Management.Pakistan journal of medical sciences · 2021Article
- Spectrum of external genital anomalies in disorders of Sex Development at Children Hospital & Institute of Child Health, Lahore, Pakistan.Pakistan journal of medical sciencesArticle
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3 authors.
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Abstract
objectiveTo determine the classification and etiological diagnosis of children presented with ambiguous genitalia/atypical genitalia according to the newer classification system of Disorder of Sex Development (DSD).
methodsThis observational, cross-sectional study was conducted at the Department of Pediatric Endocrinology and Diabetes at The Children's Hospital &Institute of Child Health, Lahore from January, 2007 to December; 2014. Files of all the children with ambiguous genitalia were retrospectively analyzed and relevant data was retrieved. All the information was recorded on predesigned proforma and analyzed accordingly.
resultsA total of 300 cases of ambiguous genitalia classified according to the new DSD classification. 46, XX DSD were 54.3% (n=163), 46, XY DSD were 43.7% (n=131), sex chromosome DSD were 2% (n=6). Among 46, XX DSD cases, the most common cause was congenital adrenal hyperplasia (97%, n=158). However, in 46, XY DSD partial androgen insensitivity/
conclusionAmbiguous genitalia have varied etiologies, 46; XXDSD found being the commonest of all, showing predominance of CAH especially salt loosing type. The early detection and prompt treatment of cases of ambiguous genitalia plays a pivotal role in the management of acute life threatening condition and gender assignment.
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