ArticleFrontiers in neuroscience2019
Pituitary Gland Functional Connectivity and BMI.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exploring the Therapeutic Potential of Targeting GH and IGF-1 in the Management of Obesity: Insights from the Interplay between These Hormones and Metabolism.International journal of molecular sciences · 2023Pooled it
- When Pathways Converge: Iron, Lipid Peroxidation, and α-Synuclein in Ferroptosis-Driven Dopaminergic Neurodegeneration.Journal of neurochemistry · 2026Review
- Neuroanatomical Reflections of Childhood Obesity: Volumetric Analysis of the Pituitary Gland and Olfactory Bulb.Children (Basel, Switzerland) · 2025Article
- Is a body mass index of less than 18.5 kg/mBMJ open · 2024Article
- Fetal programming of human energy homeostasis brain networks: Issues and considerations.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Review
- Naloxone precipitated withdrawal increases dopamine release in the dorsal striatum of opioid dependent men.Translational psychiatry · 2021Article
- Obesity and pituitary gland volume - a correlation study using three-dimensional magnetic resonance imaging.The neuroradiology journal · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The pituitary gland (PG) influences body weight through hormonal releases; however, the relation between body weight and PG's co-activities with other brain regions remains unclear. Here, we aimed to identify (1) the functional connectivity of the PG and (2) PG functional connectivity associated with body mass index by examining resting state functional magnetic resonance imaging data. Using enhanced Nathan Kline Institute-Rockland Sample, PG functional connectivity of 494 individuals was analyzed to assess in voxel-wise fashion. A negative association was found between BMI and PG functional connectivity with the orbitofrontal cortex, hippocampus, putamen, and temporal lobe. Our results show PG dysconnectivity to these regions is associated with higher BMI and implicate that the connectivity between these dopaminergic regions and PG may be associated with body weight maintenance through feeding behavior and growth.
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Registered trials
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