Evidence map›Paper›PMID 30881245›Full record

ReviewIntegrative medicine (Encinitas, Calif.)2017

Probiotics and Disease: A Comprehensive Summary-Part 5, Respiratory Conditions of the Ears, Nose, and Throat.

Margaret G Gasta, Crystal M Gossard, Christy B Williamson, Keren E Dolan, Heather J Finley, Cathleen M Burns, Emily C Parker, Jessica M Pizano, Elizabeth A Lipski

Registry-linked trialAbstract readReview
PubMed Full text at PMC
In one paragraph

Review in Integrative medicine (Encinitas, Calif.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427695 (Topical Probiotic Sinus Irrigations for the Treatment of Chronic Rhinosinusitis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05427695 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Topical Probiotic Sinus Irrigations for the Treatment of Chronic Rhinosinusitis: a Double Blinded Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2025 to 2028Enrolled60ConditionsChronic Rhinosinusitis (Diagnosis)ArmsLactobacillus sakei proBio65, Isotonic Saline Solution
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Margaret G GastaMaryland University of Integrative Health in Laurel, Maryland.
Crystal M GossardMaryland University of Integrative Health in Laurel, Maryland.
Christy B WilliamsonMaryland University of Integrative Health in Laurel, Maryland.
Keren E DolanMaryland University of Integrative Health in Laurel, Maryland.
Heather J FinleyMaryland University of Integrative Health in Laurel, Maryland.
Cathleen M BurnsMaryland University of Integrative Health in Laurel, Maryland.
Emily C ParkerMaryland University of Integrative Health in Laurel, Maryland.
Jessica M PizanoMaryland University of Integrative Health in Laurel, Maryland.
Elizabeth A LipskiMaryland University of Integrative Health in Laurel, Maryland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article series provides a literature review of the disease-specific probiotic strains studied in published clinical trials in humans and animals. The goal of the series is to provide clinically useful tools. The table design allows for quick access to supportive data and will be helpful as a guide for both researchers and clinicians. The first article (part 1) focused on mental health and neurological conditions and the second article (part 2) explored cultured and fermented foods that are commonly available in the United States. The third article (part 3) explored the relationship between bacterial strains and 2 of the most prevalent diseases we have in modern society, cardiometabolic disease and fatigue syndromes. The fourth article (part 4) elucidated the role of the microbiome in infectious diseases, and this fifth article (part 5) investigates probiotic strains on respiratory conditions that affect the ears, nose, and throat. Future articles will review conditions related to autoimmunity and dermatological conditions; the influence of the microbiome on cancer development and prognosis; gastrointestinal and genitourinary diseases associated with dysbiosis conditions; followed by an article focused on probiotic supplements. This literature review is specific to disease condition, probiotic classification, and individual strain.

Identifiers

PMID30881245
PMCPMC6419786

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.