Evidence map›Paper›PMID 30881222›Full record

ArticleMediators of inflammation2019

Coronary Artery Disease Is Associated with an Increased Amount of T Lymphocytes in Human Epicardial Adipose Tissue.

Miloš Mráz, Anna Cinkajzlová, Jana Kloučková, Zdeňka Lacinová, Helena Kratochvílová, Michal Lipš, Michal Pořízka, Petr Kopecký, Aneta Pierzynová, Tomáš Kučera and 4 more

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Miloš MrázDiabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Anna CinkajzlováDepartment of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Jana KloučkováDepartment of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Zdeňka LacinováDepartment of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Helena KratochvílováDepartment of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Michal LipšDepartment of Anaesthesiology, Resuscitation and Intensive Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Michal PořízkaDepartment of Anaesthesiology, Resuscitation and Intensive Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Petr KopeckýDepartment of Anaesthesiology, Resuscitation and Intensive Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Aneta PierzynováInstitute of Histology and Embryology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Tomáš KučeraInstitute of Histology and Embryology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Vojtěch MelenovskýCardiology Department, Cardiac Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Ilja StřížDepartment of Clinical and Transplantation Immunology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Jaroslav Lindner2nd Department of Surgery-Department of Cardiovascular Surgery, Charles University and General University Hospital, Prague, Czech Republic.
Martin HaluzíkDiabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.ORCID 0000-0002-0201-6888
Charles University · CZInstitute of Clinical and Experimental Medicine · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunocompetent cells including lymphocytes play a key role in the development of adipose tissue inflammation and obesity-related cardiovascular complications. The aim of the study was to explore the relationship between epicardial adipose tissue lymphocytes and coronary artery disease (CAD). To this end, we studied the content and phenotype of lymphocytes in peripheral blood, subcutaneous adipose tissue (SAT), and epicardial adipose tissue (EAT) in subjects with and without CAD undergoing elective cardiac surgery. Eleven subjects without CAD (non-CAD group) and 22 age-, BMI-, and HbA

Indexed as

Adipose TissueAgedB-LymphocytesCoronary Artery DiseaseFemaleFlow CytometryHumansImmunohistochemistryMaleMiddle AgedPericardiumReal-Time Polymerase Chain ReactionSubcutaneous FatT-Lymphocytes

Identifiers

PMID30881222
PMCPMC6383418
OpenAlexW2911333953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.