Evidence map›Paper›PMID 30881099›Full record

ArticleJournal of pain research2019

Who benefits from multimodal rehabilitation - an exploration of pain, psychological distress, and life impacts in over 35,000 chronic pain patients identified in the Swedish Quality Registry for Pain Rehabilitation.

Björn Gerdle, Sophia Åkerblom, Gunilla Brodda Jansen, Paul Enthoven, Malin Ernberg, Huan-Ji Dong, Britt-Marie Stålnacke, Björn O Äng, Katja Boersma

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07081737 (The Future of Pain Management), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07081737 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Future of Pain Management: Can Person-centred and Precision AI-Based Decision Support Enhance Interdisciplinary Rehabilitation for Chronic Pain?

TypeinterventionalSponsorBjorn AngRan2026 to 2029Enrolled400ConditionsPain, Chronic, Chronic Pain, Widespread, Pain ManagementArmsInterdisciplinary treatment (IDT) + Clinical Decision Support System (CDSS), Interdisciplinary treatment (IDT)
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Immersive Virtual Reality Therapy for Elderly Female Patients Undergoing Rehabilitation After Hip Arthroplasty: A Randomized Controlled Pilot Trial.Medical science monitor : international medical journal of experimental and clinical research · 2025
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  9. Pain Phenotypes in Endometriosis: A Population-Based Study Using Latent Class Analysis.BJOG : an international journal of obstetrics and gynaecology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Björn GerdlePain and Rehabilitation Centre, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden, bjorn.gerdle@liu.se.
Sophia ÅkerblomDepartment of Pain Rehabilitation, Skåne University Hospital, Lund, Sweden.
Gunilla Brodda JansenDivision of Rehabilitation Medicine, Department of Clinical Sciences, Danderyd Hospital, Stockholm, Sweden.
Paul EnthovenPain and Rehabilitation Centre, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden, bjorn.gerdle@liu.se.
Malin ErnbergDepartment of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.
Huan-Ji DongPain and Rehabilitation Centre, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden, bjorn.gerdle@liu.se.
Britt-Marie StålnackeDepartment of Community Medicine and Rehabilitation, Rehabilitation Medicine, Umeå University, Umeå, Sweden.
Björn O ÄngDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge, Sweden.
Katja BoersmaSchool of Law, Psychology and Social Work, Örebro University, Örebro, Sweden.
Linköping University · SEDanderyds sjukhus · SEKarolinska Institutet · SELund University · SEÖrebro University · SEUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic pain patients frequently suffer from psychological symptoms. There is no consensus concerning the prevalence of severe anxiety and depressive symptoms and the strength of the associations between pain intensity and psychological distress. Although an important aspect of the clinical picture is understanding how the pain condition impacts life, little is known about the relative importance of pain and psychological symptoms for individual's life impact. The aims of this study were to identify subgroups of pain patients; to analyze if pain, psychological distress, and life impact variables influence subgrouping; and to investigate how patients in the subgroups benefit from treatments.

methodsBackground variables, pain aspects (intensity/severity and spreading), psychological distress (depressive and anxiety symptoms), and two life impact variables (pain interference and perceived life control) were obtained from the Swedish Quality Registry for Pain Rehabilitation for chronic pain patients and analyzed mainly using advanced multivariate methods.

resultsBased on >35,000 patients, 35%-40% had severe anxiety or depressive symptoms. Severe psychological distress was associated with being born outside Europe (21%-24% vs 6%-8% in the category without psychological distress) and low education level (20.7%-20.8% vs 26%-27% in the category without psychological distress). Dose relationships existed between the two psychological distress variables and pain aspects, but the explained variances were generally low. Pain intensity/severity and the two psychological distress variables were significantly associated (

conclusionThe results emphasize the need to assess both pain and psychological distress and not take for granted that pain involves high psychological stress in the individual case. Not all patients benefit from MMRP. A better matching between common clinical pictures and the content of MMRPs may help improve results. We only partly found support for treatment resistance in patients with psychological distress burden.

Indexed as

anxietychronic paincontroldepressionlife impactsociodemographic

Identifiers

PMID30881099
PMCPMC6411315
OpenAlexW2918840940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.