ArticleClinical and experimental gastroenterology2019
Propofol sedation in colonoscopy: from satisfied patients to improved quality indicators.
Article in Clinical and experimental gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03922815 (Influence of Adequacy of Anaesthesia Monitoring on Both Operators' and Patients' Satisfaction in Patients Undergoing Colonoscopic Procedures), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Adequacy of Anaesthesia Monitoring on Both Operators' and Patients' Satisfaction in Patients Undergoing Colonoscopic Procedures
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Comparative Efficacy and Safety of Anesthetic and Sedative Regimens for Endoscopic Retrograde Cholangiopancreatography: A Network Meta-Analysis.Digestive diseases (Basel, Switzerland) · 2025Pooled it
- The safety of remimazolam versus propofol in gastroscopic sedation: a meta-analysis.BMC anesthesiology · 2024Pooled it
- Knowledge, attitudes, and practices toward bowel preparation for sedation-assisted colonoscopy among patients with digestive disorders: a structural equation modeling analysis.BMC gastroenterology · 2026Article
- The impact of sedation on adenoma and polyp detection rates in colonoscopy: an evidence-informed narrative review.Translational gastroenterology and hepatology · 2026Review
- Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy.Anesthesiology and pain medicine · 2025Article
- Association between Colonoscopy Sedation Type and Polyp Detection: A Registry-based Cohort Study.Anesthesiology · 2024Observational
- Propofol sedation does not improve measures of colonoscopy quality but increase cost - findings from a large population-based cohort study.EClinicalMedicine · 2024Article
- Impact of different doses of esketamine on the incidence of hypotension in propofol-based sedation for colonoscopy: a randomized controlled trial.Therapeutic advances in drug safety · 2024Article
- Adequacy of Anesthesia Guidance for Colonoscopy Procedures.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Confocal laser endomicroscopy under propofol-based sedation for early gastric cancer and pre-cancerous lesions is associated with better diagnostic accuracy: a retrospective cohort study in China.BMC anesthesiology · 2021Article
- Autonomous Nervous Response During Sedation in Colonoscopy and the Relationship With Clinician Satisfaction.Frontiers in medicine · 2021Article
- Impact of propofol sedation versus opioid/benzodiazepine sedation on colonoscopy outcomes: a systematic review with meta-analysis.Endoscopy international open · 2020Article
- The Impact of Sedation on Adenoma Detection Rate and Cecal Intubation Rate in Colonoscopy.Gastroenterology research and practice · 2020Article
- Can Bispectral Index Monitoring (EEG) be an Early Predictor of Respiratory Depression under Deep Sedation during Endoscopic Retrograde Cholangiopancreatography?Sisli Etfal Hastanesi tip bulteni · 2020Article
- Caffeine reverses the unconsciousness produced by light anesthesia in the continued presence of isoflurane in rats.PloS one · 2020Article
- Comparative Study of Moderate Sedation with Propofol Versus Propofol Combined with Midazolam for Ambulatory Care Digestive Endoscopic Procedures.Current health sciences journalArticle
- Is routine terminal ileum intubation justified during screening colonoscopy? Evidence from a regional screening program.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPropofol-mediated sedation is safe and clearly associated with increased patient satisfaction. However, whether it results in a favorable effect on colonoscopy outcomes and performance compared to standard sedation with benzodiazepines/opiates remains unclear.
objectivesTo determine the effect of propofol-mediated sedation on colonoscopy-quality measures compared to traditional sedation.
methodsA large cohort of 44,794 patients who had undergone sedated colonoscopies were included. Colonoscopy-quality indicators were examined in benzodiazepine/opiate-sedated patients and compared with a propofol-mediated sedation group. Adjustment for potential confounders, such as age, sex, quality of bowel preparation, procedural setting, and indication was performed.
resultsPatients who received propofol-mediated sedation were more likely, and in a dose-dependent manner, to have an enhanced polyp-detection rate (22.8% vs 20.9%,
conclusionPropofol-mediated sedation during colonoscopy is associated with better examination performance and improved outcomes. Further prospective or randomized trials to support these findings are warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.