Evidence map›Paper›PMID 30881059›Full record

ArticleInfection and drug resistance2019

Genetic basis for metronidazole and clarithromycin resistance in

Seyed Jalal Hashemi, Ahmad Farajzadeh Sheikh, Hamed Goodarzi, Mohammad Jaafar Yadyad, Seyed Saeid Seyedian, Sajad Aslani, Mohammad-Ali Assarzadegan

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Antibiotic Resistance Identification Among the Patients withMiddle East journal of digestive diseases · 2025
    Article
  6. RdxA-independent mechanism ofFrontiers in microbiology · 2025
    Article
  7. Diseases (Basel, Switzerland) · 2024
    Review
  8. International journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
  11. Antibiotic Resistance Rates forMicroorganisms · 2023
    Article
  12. Review
  13. Review
  14. Evolution ofAntibiotics (Basel, Switzerland) · 2023
    Review
  15. The Lancet regional health. Western Pacific · 2022
    Article
  16. Antioxidants (Basel, Switzerland) · 2021
    Article
  17. Trends inMicrobial genomics · 2020
    Review
  18. Article
  19. Phenotypic and Genotypic Antibiotic Resistance Patterns inFrontiers in cellular and infection microbiology · 2020
    Article
  20. Genotype profiles ofTherapeutic advances in gastroenterology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Seyed Jalal HashemiInfectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, goodarzi200055@yahoo.com.
Ahmad Farajzadeh SheikhInfectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, goodarzi200055@yahoo.com.
Hamed GoodarziInfectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, goodarzi200055@yahoo.com.
Mohammad Jaafar YadyadInfectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, goodarzi200055@yahoo.com.
Seyed Saeid SeyedianAlimentary Tract Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Sajad AslaniStudent Research Committee, Kerman University of Medical Sciences, Kerman, Iran.
Mohammad-Ali AssarzadeganImmunology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ahvaz Jundishapur University of Medical Sciences · IRIran University of Medical Sciences · IRKerman University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate the antimicrobial resistance and genetic basis for metronidazole (Mtz) and clarithromycin (Cla) resistance in strains of PATIENTS AND

methodsA total of 157

resultsAmong 157

conclusionMutational inactivation and efflux pump overexpression are two mechanisms that increase the resistance to

Indexed as

drug resistanceefflux pumpgenetic mutationsH. pylori

Identifiers

PMID30881059
PMCPMC6404679
OpenAlexW2918289110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.