Evidence map›Paper›PMID 30880984›Full record

ArticleInternational journal of nanomedicine2019

Nanosilver/poly (dl-lactic-co-glycolic acid) on titanium implant surfaces for the enhancement of antibacterial properties and osteoinductivity.

Xuemin Zeng, Shijiang Xiong, Shaoyang Zhuo, Chunpeng Liu, Jie Miao, Dongxu Liu, Hengxiao Wang, Yueying Zhang, Chunling Wang, Yi Liu

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  8. An Updated Review on Silver Nanoparticles in Biomedicine.Nanomaterials (Basel, Switzerland) · 2020
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Xuemin ZengShandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, People's Republic of China, yiliu@sdu.edu.cn; wangchl@sdu.edu.cn.
Shijiang XiongShandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, People's Republic of China, yiliu@sdu.edu.cn; wangchl@sdu.edu.cn.
Shaoyang ZhuoShandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, People's Republic of China, yiliu@sdu.edu.cn; wangchl@sdu.edu.cn.
Chunpeng LiuShandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, People's Republic of China, yiliu@sdu.edu.cn; wangchl@sdu.edu.cn.
Jie MiaoDepartment of Stomatology, The 5th People's Hospital of Jinan, Jinan, People's Republic of China.
Dongxu LiuShandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, People's Republic of China, yiliu@sdu.edu.cn; wangchl@sdu.edu.cn.
Hengxiao WangDepartment of Experimental Pathology, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, People's Republic of China.
Yueying ZhangDepartment of Experimental Pathology, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, People's Republic of China.
Chunling WangShandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, People's Republic of China, yiliu@sdu.edu.cn; wangchl@sdu.edu.cn.
Yi LiuShandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, People's Republic of China, yiliu@sdu.edu.cn; wangchl@sdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite titanium (Ti) implants have been commonly used in the medical device field due to their superior biocompatibility, implant-associated bacterial infection remains a major clinical complication. Nanosilver, an effective antibacterial agent against a wide spectrum of bacterial strains, with a low-resistance potential, has attracted much interest too. Incorporation of nanosilver on Ti implants may be a promising approach to prevent biofilm formation. Purpose: The objective of the study was to investigate the antibacterial effects and osteoinductive properties of nanosilver/poly (dl-lactic-co-glycolic acid)-coated titanium (NSPTi). Methods: Gram-positive methicillin-resistant Results: In vitro, bacterial adhesion to the 2% NSPTi was significantly inhibited and <1% of adhered bacteria survived after 24 hours. In vitro, the average colony-forming units (CFU)/g ratios in the 2% NSPTi with 10 Conclusion: NSPTi implants have simultaneous antibacterial and osteoinductive activities and therefore have the potential in clinical applications.

Indexed as

Prostheses and ImplantsAnimalsAnti-Bacterial AgentsCell LineCoated Materials, BiocompatibleColony Count, MicrobialHumansKineticsMaleMethicillin-Resistant Staphylococcus aureusMiceMicrobial Sensitivity TestsNanoparticlesOsseointegrationOsteogenesisPolylactic Acid-Polyglycolic Acid CopolymerAnti-Bacterial AgentsCoated Materials, BiocompatiblePolylactic Acid-Polyglycolic Acid CopolymerSilverTitaniumantimicrobialinfectionosteogenesissilver nanoparticlesTi

Identifiers

PMID30880984
PMCPMC6417851

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.