ArticleClinical ophthalmology (Auckland, N.Z.)2019
Transepithelial accelerated versus conventional corneal collagen crosslinking in patients with keratoconus: a comparative study.
Article in Clinical ophthalmology (Auckland, N.Z.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Epithelium-on versus epithelium-off corneal collagen crosslinking for keratoconus: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Pooled it
- Transepithelial versus epithelium-off corneal crosslinking for progressive keratoconus.The Cochrane database of systematic reviews · 2021Pooled it
- Transepithelial corneal cross-linking: a review.International ophthalmology · 2026Review
- Transepithelial Accelerated Crosslinking for Progressive Keratoconus: A Critical Analysis of Medium-Term Treatment Outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Current approaches in the management of patients with keratoconus.Medicine and pharmacy reports · 2022Review
- Best Fit Sphere Back and Adjusted Maximum Elevation of Corneal Back Surface as Novel Predictors of Keratoconus Progression.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index.Diagnostics (Basel, Switzerland) · 2021Article
- Keratoconus enlargement as a predictor of keratoconus progression.Scientific reports · 2021Article
- Corneal collagen cross-linking epithelium-on vs. epithelium-off: a systematic review and meta-analysis.Eye and vision (London, England) · 2021Review
- Comparison of corneal biological parameters between transepithelial and epithelium-off corneal cross-linking in keratoconus.International journal of ophthalmology · 2021Article
- Comparison of Standard and Transepithelial Corneal Cross-Linking for the Treatment of Keratoconus: A Meta-analysis.Journal of ophthalmology · 2021Article
- Increased choroidal thickness is not a disease progression marker in keratoconus.Scientific reports · 2020Observational
- Efficacy of Standard and Accelerated (10 Minutes) Corneal Crosslinking in Keratoconus Stabilization.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Long-Term Visual, Refractive and Topographic Outcomes of "Epi-off" Corneal Collagen Cross-Linking in Pediatric Keratoconus: Standard versus Accelerated Protocol.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Transepithelial Accelerated Corneal Collagen Cross-Linking: Two-Year Results.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo systematically compare the efficacy of transepithelial accelerated corneal collagen crosslinking (TE-ACXL) with conventional corneal collagen crosslinking (C-CXL) in patients with progressive keratoconus.
methodsEyes of patients with progressive keratoconus who were treated with C-CXL (3 mW/cm
resultsThe study enrolled 26 eyes of which 16 had TE-ACXL and 10 had C-CXL. Both groups were comparable at baseline and 12 months in terms of BCVA (
conclusionBoth TE-ACXL and C-CXL were similarly effective. Further follow-up is required to determine whether these techniques are comparable in the long-term.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.