Evidence map›Paper›PMID 30880882›Full record

ArticleSupramolecular chemistry2017

Efficient Fluorescence Detection of Aromatic Toxicants and Toxicant Metabolites in Human Breast Milk.

Dana J DiScenza, Julie Lynch, Molly Verderame, Nicole Serio, Lindsey Prignano, Lauren Gareau, Mindy Levine

Open access · greenAbstract read
In one paragraph

Article in Supramolecular chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Detection of anabolic steroidsRSC advances · 2020
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dana J DiScenzaDepartment of Chemistry, University of Rhode Island, 140 Flagg Road, Kingston, RI 02881.
Julie LynchDepartment of Chemistry, University of Rhode Island, 140 Flagg Road, Kingston, RI 02881.
Molly VerderameDepartment of Chemistry, University of Rhode Island, 140 Flagg Road, Kingston, RI 02881.
Nicole SerioDOE Golden Field Office, Environmental Oversight Office, 15013 Denver West Parkway, Golden, Colorado 80401.
Lindsey PrignanoDepartment of Chemistry & Biochemistry, Worcester Polytechnic Institute, 60 Prescott Street, Worcester, MA 01609.
Lauren GareauSchool of Public Health, Boston University, 715 Albany Street, Boston, MA 02118.
Mindy LevineDepartment of Chemistry, University of Rhode Island, 140 Flagg Road, Kingston, RI 02881.
University of Rhode Island · USBoston University · USWorcester Polytechnic Institute · US

Funding

(PQA4) Detecting carcinogens in complex environments via energy transferR21CA185435 · NCI · UNIVERSITY OF RHODE ISLAND · PI LEVINE, MINDY · 2014 to 2015
$341k
NCI NIH HHS R21 CA185435
6 · The paper itself

Abstract

Once chemical contaminants are released into the environment, there are a number of concerns that arise regarding the environmental persistence of the contaminants, their known and suspected toxicities, and their potential disruption to the ecosystem. One class of contaminants that is of continuing concern is polycyclic aromatic hydrocarbons (PAHs), persistent organic pollutants that are significant components of oil spills. PAHs have been found in the breast milk of nursing mothers living in oil spill affected regions, and can harm the nursing children. We report herein the sensitive and selective detection of 10 PAHs and PAH metabolites in human breast milk using fluorescence energy transfer from the PAH to a high quantum yield fluorophore, and array-based statistical analyses of the resulting fluorescence responses. This detection system was able to separate and identify the PAHs with 100% success in human breast milk and at concentrations as low as 0.17 μM. These results have significant implications in public health and in the monitoring and mitigation of environmental disasters.

Indexed as

cyclodextrinenergy transferfluorescence detectionpolycyclic aromatic hydrocarbons

Identifiers

PMID30880882
PMCPMC6420232
OpenAlexW2726865370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.