ArticleChemistry of materials : a publication of the American Chemical Society2017
Protein-Imprinted Polymers: The Shape of Things to Come?
Article in Chemistry of materials : a publication of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The trial behind it
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Who cites it
45 citing papers in PubMed, 143 citations in OpenAlex.
- Epitope-Imprinted Polymers for Selective Recognition of Bacterial Proteins: From Design to Analytical Applications.ACS measurement science au · 2026Review
- Controlled Photoiniferter RAFT-Based Development of Linear Polymers Induced by the Presence of a Peptide to Produce Synthetic Antibody Substitutes Applicable to Immunofluorescence Imaging Techniques.Analytical chemistry · 2026Article
- Ion-imprinted polymer-based sensors for toxic metal-ion detection in water: coordination chemistry, transduction strategies, and environmental applications.Frontiers in chemistry · 2026Review
- Core/shell molecularly imprinted nanoparticles: optimized synthesis and application in QCM-D biosensing.RSC advances · 2025Article
- Magnetite Nanoparticles with High Affinity Toward Target Protein for Efficient and Facile Bio-Separation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- An epitope imprinted electrochemical sensor for highly sensitive and selective determination of prostate-specific antigen.Mikrochimica acta · 2024Article
- Rational design based on multi-monomer simultaneous docking for epitope imprinting of SARS-CoV-2 spike protein.Scientific reports · 2024Article
- Electrochemical detection of poly(3-hydroxybutyrate) production from Burkholderia glumae MA13 using a molecularly imprinted polymer-reduced graphene oxide modified electrode.Mikrochimica acta · 2024Article
- Imprinted Polymers on the Route to Plastibodies for Biomacromolecules (MIPs), Viruses (VIPs), and Cells (CIPs).Advances in biochemical engineering/biotechnology · 2024Review
- Mobile Point-of-Care Device Using Molecularly Imprinted Polymer-Based Chemosensors Targeting Interleukin-1β Biomarker.Biosensors · 2023Article
- Elucidation of the Binding Orientation in α2,3- and α2,6-Linked Neu5Ac-Gal Epitopes toward a Hydrophilic Molecularly Imprinted Monolith.ACS omega · 2023Article
- Imprinted Hydrogel Nanoparticles for Protein Biosensing: A Review.ACS sensors · 2023Review
- Electrochemical and thermal detection of allergenic substance lysozyme with molecularly imprinted nanoparticles.Analytical and bioanalytical chemistry · 2023Article
- Highly Selective Aptamer-Molecularly Imprinted Polymer Hybrids for Recognition of SARS-CoV-2 Spike Protein Variants.Global challenges (Hoboken, NJ) · 2023Article
- Rational In Silico Design of Molecularly Imprinted Polymers: Current Challenges and Future Potential.International journal of molecular sciences · 2023Review
- Polymeric Membranes for Biomedical Applications.Polymers · 2023Review
- Molecular Level Sucrose Quantification: A Critical Review.Sensors (Basel, Switzerland) · 2022Review
- Picomolar or beyond Limit of Detection Using Molecularly Imprinted Polymer-Based Electrochemical Sensors: A Review.Biosensors · 2022Review
- Bio-Inspired Imprinting Materials for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Differential Refractometric Biosensor for Reliable Human IgG Detection: Proof of Concept.Biosensors · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The potential to develop materials with antibody-like molecular recognition properties has helped sustain interest in protein-imprinted polymers over the past several decades. Unfortunately, despite persistent research, the field of noncovalent protein imprinting has seen limited success in terms of achieving materials with high selectivity and high affinity. In this Perspective, important yet sometimes overlooked aspects of the imprinting and binding processes are reviewed to help understand why there has been limited success. In particular, the imprinting and binding processes are viewed through the scope of free radical polymerization and hydrogel swelling theories to underscore the complexity of the synthesis and behavior of protein-imprinted polymers. Additionally, we review the metrics of success commonly used in protein imprinting literature (i.e., adsorption capacity, imprinting factor, and selectivity factor) and consider the relevance of each to the characterization of an imprinted polymer's recognition characteristics. Throughout, common shortcomings are highlighted, and experiments that could help verify or disprove the efficacy of noncovalent protein imprinting are discussed.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.