Evidence map›Paper›PMID 30880291›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2020

Dynamic Contrast-enhanced Area-detector CT vs Dynamic Contrast-enhanced Perfusion MRI vs FDG-PET/CT: Comparison of Utility for Quantitative Therapeutic Outcome Prediction for NSCLC Patients Undergoing Chemoradiotherapy.

Shinichiro Seki, Yasuko Fujisawa, Masao Yui, Yuji Kishida, Hisanobu Koyama, Shigeharu Ohyu, Naoki Sugihara, Takeshi Yoshikawa, Yoshiharu Ohno

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04034667 (Clinical Study of CT and MR in Prediction of Driving Genes and Response in Patients With Lung Cancer), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04034667 unknown statusnot on this map

Clinical Study of CT and MR in Prediction of Driving Genes and Response in Patients With Lung Cancer

TypeobservationalSponsorHenan Cancer HospitalRan2019 to 2023Enrolled400ConditionsLung Cancer Squamous Cell, CT, Genes, ResponseArmsNo intervention
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Functional Pulmonary Imaging.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Shinichiro SekiDivision of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine.
Yasuko FujisawaCanon Medical Systems Corporation.
Masao YuiCanon Medical Systems Corporation.
Yuji KishidaDivision of Radiology, Department of Radiology, Kobe University Graduate School of Medicine.
Hisanobu KoyamaDivision of Radiology, Department of Radiology, Kobe University Graduate School of Medicine.
Shigeharu OhyuCanon Medical Systems Corporation.
Naoki SugiharaCanon Medical Systems Corporation.
Takeshi YoshikawaDivision of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine.
Yoshiharu OhnoDivision of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine.
Canon (Japan) · JPKobe University · JPAdvanced Imaging Research (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo directly compare the utility for therapeutic outcome prediction of dynamic first-pass contrast-enhanced (CE)-perfusion area-detector computed tomography (ADCT), MR imaging assessed with the same mathematical method and 2-[fluorine-18]-fluoro-2-deoxy-d-glucose-positron emission tomography combined with CT (PET/CT) for non-small cell lung cancer (NSCLC) patients treated with chemoradiotherapy. MATERIALS AND

methodsForty-three consecutive stage IIIB NSCLC patients, consisting of 25 males (mean age ± standard deviation: 66.6 ± 8.7 years) and 18 females (66.4 ± 8.2 years) underwent PET/CT, dynamic CE-perfusion ADCT and MR imaging, chemoradiotherapy, and follow-up examination. In each patient, total, pulmonary arterial, and systemic arterial perfusions were calculated from both perfusion data and SUV

resultsArea under the curve (Az) for total perfusion on ADCT was significantly larger than that of pulmonary arterial perfusion (P < 0.05). Az of total perfusion on MR imaging was significantly larger than that of pulmonary arterial perfusion (P < 0.05). Mean OS of responder and non-responder groups were significantly different for total and systemic arterial (P < 0.05) perfusion.

conclusionDynamic first-pass CE-perfusion ADCT and MR imaging as well as PET/CT are useful for early prediction of treatment response by NSCLC patients treated with chemoradiotherapy.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMagnetic Resonance ImagingPositron Emission Tomography Computed TomographyTomography, X-Ray ComputedAgedFemaleFluorodeoxyglucose F18HumansImage Interpretation, Computer-AssistedKaplan-Meier EstimateMaleMiddle AgedTreatment OutcomeFluorodeoxyglucose F18computed tomographymagnetic resonance imagingnon-small cell lung cancerpositron emission tomography combined with computed tomographytherapeutic effect

Identifiers

PMID30880291
PMCPMC7067914
OpenAlexW2922015163

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.