Evidence map›Paper›PMID 30879732›Full record

Trial reportThe Journal of pediatrics2019

Clamping the Umbilical Cord in Premature Deliveries (CUPiD): Neuromonitoring in the Immediate Newborn Period in a Randomized, Controlled Trial of Preterm Infants Born at <32 Weeks of Gestation.

Daragh Finn, Deirdre Hayes Ryan, Andreea Pavel, John M O'Toole, Vicki Livingstone, Geraldine B Boylan, Louise C Kenny, Eugene M Dempsey

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in The Journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 9 pooled it
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 9 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Daragh FinnDepartment of Pediatrics and Child Health, Cork University Maternity Hospital, Cork Ireland; Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland. Electronic address: daragh.finn@hse.ie.
Deirdre Hayes RyanIrish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland; Department of Obstetrics, Cork University Maternity Hospital, Cork Ireland.
Andreea PavelDepartment of Pediatrics and Child Health, Cork University Maternity Hospital, Cork Ireland; Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland.
John M O'TooleDepartment of Pediatrics and Child Health, Cork University Maternity Hospital, Cork Ireland; Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland.
Vicki LivingstoneDepartment of Pediatrics and Child Health, Cork University Maternity Hospital, Cork Ireland; Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland.
Geraldine B BoylanDepartment of Pediatrics and Child Health, Cork University Maternity Hospital, Cork Ireland; Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland.
Louise C KennyIrish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland; Department of Obstetrics, Cork University Maternity Hospital, Cork Ireland.
Eugene M DempseyDepartment of Pediatrics and Child Health, Cork University Maternity Hospital, Cork Ireland; Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland.
University College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare cerebral activity and oxygenation in preterm infants (<32 weeks of gestation) randomized to different cord clamping strategies. STUDY

designPreterm infants born at <32 weeks of gestation were randomized to immediate cord clamping, umbilical cord milking (cord stripped 3 times), or delayed cord clamping for 60 seconds with bedside resuscitation. All infants underwent electroencephalogram (EEG) and cerebral near infrared spectroscopy for the first 72 hours after birth. Neonatal primary outcome measures were quantitative measures of the EEG (17 features) and near infrared spectroscopy over 1-hour time frames at 6 and 12 hours of life.

resultsForty-five infants were recruited during the study period. Twelve infants (27%) were randomized to immediate cord clamping, 19 (42%) to umbilical cord milking, and 14 (31%) to delayed cord clamping with bedside resuscitation. There were no significant differences between groups for measures of EEG activity or cerebral near infrared spectroscopy. Three of the 45 infants (6.7%) were diagnosed with severe IVH (2 in the immediate cord clamping group, 1 in the umbilical cord milking group; P = .35).

conclusionsThere were no differences in cerebral EEG activity and cerebral oxygenation values between cord management strategies at 6 and 12 hours.

trial registrationISRCTN92719670.

Indexed as

Cerebral HemorrhageConstrictionElectroencephalographyFemaleGestational AgeHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesMaleSpectroscopy, Near-InfraredTime FactorsUmbilical Corddelayed cord clampingEEGimmediate cord clampingneonatalNIRSumbilical cord milking

Identifiers

PMID30879732
OpenAlexW2922205901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.