Evidence map›Paper›PMID 30879410›Full record

ArticleCell adhesion & migration2019

T lymphocytes migrate upstream after completing the leukocyte adhesion cascade.

Nicholas R Anderson, Alexander Buffone, Daniel A Hammer

Abstract read
In one paragraph

Article in Cell adhesion & migration, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  4. Article
  5. Article
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  7. Review
  8. Article
  9. Keratocytes migrate against flow with a roly-poly-like mechanism.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Integrin crosstalk allows CD4+ T lymphocytes to continue migrating in the upstream direction after flow.Integrative biology : quantitative biosciences from nano to macro · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicholas R Andersona Department of Chemical and Biomolecular Engineering , University of Pennsylvania , Philadelphia , PA , USA.ORCID 0000-0001-6027-9101
Alexander Buffonea Department of Chemical and Biomolecular Engineering , University of Pennsylvania , Philadelphia , PA , USA.ORCID 0000-0003-0303-0152
Daniel A Hammera Department of Chemical and Biomolecular Engineering , University of Pennsylvania , Philadelphia , PA , USA.ORCID 0000-0002-3522-3154

Funding

The mechanochemical control of T-cell directional migration under flowR01GM123019 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI HAMMER, DANIEL A · 2017 to 2020
$1.7M
NIGMS NIH HHS R01 GM123019
6 · The paper itself

Abstract

The leukocyte adhesion cascade is of critical importance for both the maintenance of immune homeostasis and the ability of immune cells to perform effector functions. Here, we present data showing CD4

Indexed as

Cell AdhesionCell MovementCells, CulturedEndothelium, VascularHumansIntercellular Adhesion Molecule-1LeukocytesT-LymphocytesVascular Cell Adhesion Molecule-1ICAM1 protein, humanIntercellular Adhesion Molecule-1Vascular Cell Adhesion Molecule-1CXCL12Directional migrationFlow chamberICAM-1P-selectinSDF-1α

Identifiers

PMID30879410
PMCPMC6527389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.