Evidence map›Paper›PMID 30879408›Full record

ArticleJournal of the American Heart Association2019

Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study.

Anthony O Etyang, Sailoki Kapesa, Emily Odipo, Evasius Bauni, Catherine Kyobutungi, Marwah Abdalla, Paul Muntner, Solomon K Musani, Alex Macharia, Thomas N Williams and 3 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Mendelian Randomization and Infection: Pitfalls and Promises.The Journal of infectious diseases · 2025
    Review
  4. Article
  5. Immune and inflammatory mechanisms in hypertension.Nature reviews. Cardiology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Neurological impairment and disability in children in rural Kenya.Developmental medicine and child neurology · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

Anthony O Etyang1 KEMRI-Wellcome Trust Research Programme Kilifi Kenya.
Sailoki Kapesa1 KEMRI-Wellcome Trust Research Programme Kilifi Kenya.
Emily Odipo1 KEMRI-Wellcome Trust Research Programme Kilifi Kenya.
Evasius Bauni1 KEMRI-Wellcome Trust Research Programme Kilifi Kenya.
Catherine Kyobutungi3 African Population and Health Research Centre Nairobi Kenya.
Marwah Abdalla4 Columbia University Medical Center New York NY.
Paul Muntner5 University of Alabama at Birmingham AL.
Solomon K Musani6 University of Mississippi Medical Center Jackson MS.
Alex Macharia1 KEMRI-Wellcome Trust Research Programme Kilifi Kenya.
Thomas N Williams1 KEMRI-Wellcome Trust Research Programme Kilifi Kenya.
J Kennedy Cruickshank8 King's College London United Kingdom.
Liam Smeeth2 London School of Hygiene and Tropical Medicine London United Kingdom.
J Anthony G Scott1 KEMRI-Wellcome Trust Research Programme Kilifi Kenya.
Kenya Medical Research Institute · KEAfrican Population and Health Research Center · KEColumbia University Irving Medical Center · USImperial College London · GBJackson Memorial Hospital · USKing's College London · GBLondon School of Hygiene & Tropical Medicine · GBUniversity of Alabama at Birmingham · US

Funding

Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS R01 HL117323Wellcome Trust 202800/Z/16/Z
6 · The paper itself

Abstract

Background Malaria exposure in childhood may contribute to high blood pressure ( BP ) in adults. We used sickle cell trait ( SCT ) and α

Indexed as

AdultBlood PressureFemaleHumansHypertensionKenyaMalariaMaleMendelian Randomization AnalysisPrevalenceYoung Adultambulatory blood pressure monitoringhigh blood pressurehypertensionmalariaMendelian randomizationsickle cell diseasesickle cell traitthalassemia

Identifiers

PMID30879408
PMCPMC6475058
OpenAlexW2921377907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.