Evidence map›Paper›PMID 30879276›Full record

ArticleBiomolecules & therapeutics2019

Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model.

Janeesh Plakkal Ayyappan, Kezia Lizardo, Sean Wang, Edward Yurkow, Jyothi F Nagajyothi

Open access · greenAbstract read
In one paragraph

Article in Biomolecules & therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  6. Sex Differences in Cardiac Pathology of SARS-CoV2 Infected andFrontiers in cardiovascular medicine · 2022
    Article
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Janeesh Plakkal AyyappanDepartment of Microbiology, Biochemistry and Molecular Genetics, Public Health Research Institute, New Jersey Medical School, Newark, NJ 07103, USA.
Kezia LizardoDepartment of Microbiology, Biochemistry and Molecular Genetics, Public Health Research Institute, New Jersey Medical School, Newark, NJ 07103, USA.
Sean WangRutgers Molecular Imaging Center, Piscataway, NJ 08854, USA.
Edward YurkowRutgers Molecular Imaging Center, Piscataway, NJ 08854, USA.
Jyothi F NagajyothiDepartment of Microbiology, Biochemistry and Molecular Genetics, Public Health Research Institute, New Jersey Medical School, Newark, NJ 07103, USA.
Rutgers New Jersey Medical SchoolImaging Center · USRutgers, The State University of New Jersey · US

Funding

Pathogenic contribution of lipid homeostasis to chagasic CardiomyopathyR01HL122866 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI NAGAJYOTHI, JYOTHI FALGUNI · 2015 to 2018
$1.6M
NHLBI NIH HHS R01 HL122866
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

2-AminopurineCardiomyopathyChagas diseaseEndoplasmic reticulum stressMitochondrial stress

Identifiers

PMID30879276
PMCPMC6609105
OpenAlexW2886177877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.