Evidence map›Paper›PMID 30879209›Full record

ArticleAIDS and behavior2019

Implementing an Updated "Break the Cycle" Intervention to Reduce Initiating Persons into Injecting Drug Use in an Eastern European and a US "opioid epidemic" Setting.

Don Des Jarlais, Anneli Uuskula, Ave Talu, David M Barnes, Mait Raag, Kamyar Arasteh, Greete Org, Donna Demarest, Jonathan Feelemyer, Hayley Berg and 1 more

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Don Des JarlaisSocial and Behavioral Sciences, College of Global Public Health, New York University, 665 Broadway, 8th Floor, New York, NY, 10003, USA. don.desjarlais@nyu.edu.ORCID http://orcid.org/0000-0002-0157-8168
Anneli UuskulaDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Ave TaluDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
David M BarnesSocial and Behavioral Sciences, College of Global Public Health, New York University, 665 Broadway, 8th Floor, New York, NY, 10003, USA.
Mait RaagDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Kamyar ArastehSocial and Behavioral Sciences, College of Global Public Health, New York University, 665 Broadway, 8th Floor, New York, NY, 10003, USA.
Greete OrgDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Donna DemarestCHASI: Community Health Action of Staten Island, New York, USA.
Jonathan FeelemyerDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA.
Hayley BergSocial and Behavioral Sciences, College of Global Public Health, New York University, 665 Broadway, 8th Floor, New York, NY, 10003, USA.
Susan TrossHIV Center for Clinical and Behavioral Studies at The New York State Psychiatric Institute and Columbia University, New York, USA.
University of Tartu · EENew York University · USCommunity Health Action of Staten Island · USIcahn School of Medicine at Mount Sinai · USNew York Psychoanalytic Society and Institute · USYork University · US

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI LINDA M COLLINS · 1998 to 2026
$38.9M
Combined prevention to reduce initiation into injecting drug useDP1DA039542 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C · 2015 to 2019
$4.1M
Ministère de l'Education Nationale, de la Formation professionnelle, de l'Enseignement Supérieur et de la Recherche Scientifique (MA) IUT34-17NIDA NIH HHS 5-DP1-DA039542NIDA NIH HHS DP1 DA039542
6 · The paper itself

Abstract

We tested the hypothesis that an updated "Break the Cycle" (BtC) intervention, based in social cognitive theory and motivational interviewing, would reduce the likelihood that current persons who inject drugs (PWID) would assist persons who do not inject drugs (non-PWID) with first injections in Tallinn, Estonia and Staten Island, New York City. 402 PWID were recruited, a baseline interview covering demographics, drug use, and assisting non-PWID with first drug injections was administered, followed by BtC intervention. 296 follow-up interviews were conducted 6 months post-intervention. Percentages assisting with first injections declined from 4.7 to 1.3% (73% reduction) in Tallinn (p < 0.02), and from 15 to 6% (60% reduction) in Staten Island (p < 0.05). Persons assisted with first injections declined from 11 to 3 in Tallinn (p = 0.02) and from 32 to 13 in Staten Island. (p = 0.024). Further implementation research on BtC interventions is urgently needed where injecting drug use is driving HIV/HCV epidemics and areas experiencing opioid epidemics.

Indexed as

EpidemicsAdultAnalgesics, OpioidDrug UsersEstoniaFemaleHumansMaleMiddle AgedMotivational InterviewingNew York CityOpioid-Related DisordersRisk-TakingSubstance Abuse, IntravenousAnalgesics, OpioidBreak the cycleFirst injectionHIVInitiationInjecting drug useOpioid epidemic

Identifiers

PMID30879209
PMCPMC6746607
OpenAlexW2921536103

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.