Evidence map›Paper›PMID 30879204›Full record

SynthesisClinical rheumatology2019

Podocytic infolding glomerulopathy: two new cases with connective tissue disease and literature review.

Ting Zhang, Wenjia Sun, Jing Xue, Jiaxi Chen, Qifeng Jiang, Lijun Mou, Hengjian Du

Abstract readCase ReportsSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. IgA nephropathy with podocytic infolding glomerulopathy.Chronic diseases and translational medicine · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Podocyte Infolding Glomerulopathy, First Case Report From North America.Canadian journal of kidney health and disease · 2021
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ting ZhangDivision of Rheumatology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, No.88, Jiefang Road, Shangcheng District, Hangzhou, 310005, Zhejiang, People's Republic of China.
Wenjia SunDivision of Rheumatology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, No.88, Jiefang Road, Shangcheng District, Hangzhou, 310005, Zhejiang, People's Republic of China.
Jing XueDivision of Rheumatology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, No.88, Jiefang Road, Shangcheng District, Hangzhou, 310005, Zhejiang, People's Republic of China.
Jiaxi ChenDivision of Nephrology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, No.88, Jiefang Road, Shangcheng District, Hangzhou, 310005, Zhejiang, People's Republic of China.
Qifeng JiangDivision of Renal pathology, Guangzhou Kingmed Diagnostic Laboratory Ltd, No10. three helix Road, Guangzhou international Biological Island, Guangzhou, 510220, Guangdong, People's Republic of China.
Lijun Mou *Division of Nephrology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, No.88, Jiefang Road, Shangcheng District, Hangzhou, 310005, Zhejiang, People's Republic of China. moulj511@zju.edu.cn.
Hengjian Du *Division of Geriatric Infectious Disease, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, No.32 West Second Section First Ring Road, Chengdu, 610072, Sichuan, People's Republic of China. duhengjian@sina.com.

Funding

Zhejiang Province Public Welfare Technology Application Research Project 2017C33093
6 · The paper itself

Abstract

Podocytic infolding glomerulopathy (PIG) is a newly proposed disease entity, and only 29 cases have been reported worldwide so far, characterized by microspheres or microtubular structures or both associated with podocytic infolding into the glomerular basement membrane (GBM) on electron microscopy. We present two new cases of PIG with connective tissue disease (CTD), one with primary Sjögren's syndrome and the other with systemic lupus erythematosus (SLE), and make a systemic review of the literature. In the entire 31 patients of PIG, 24 (77.42%) were women and seven (22.58%) were men, with an average age of 41.2 ± 15.2 (ranging from 14 to 79) years old. Almost two-thirds of patients (67.74%) were diagnosed with CTD, in which 76.19% were SLE. All patients presented with proteinuria and six (19.35%) patients were accompanied with hematuria. Serum creatinine was elevated in six (19.35%) patients. Pathological findings of all patients were consistent with PIG characteristics, and four patients with repeated renal biopsies further provided profound insights.

Indexed as

AdultCreatinineFemaleGlomerular Basement MembraneHematuriaHumansKidney DiseasesLupus Erythematosus, SystemicPodocytesProteinuriaSjogren's SyndromeYoung AdultCreatininePodocytic infolding glomerulopathySjögren’s syndromeSystemic lupus erythematosus

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.