Evidence map›Paper›PMID 30879105›Full record

ArticleUrolithiasis2019

Cancer as a risk factor for urinary tract calculi: a retrospective cohort study using 'The Health Improvement Network' : Cancer and urinary tract calculi.

Ankush Mittal, Motaz Elmahdy Hassan, Joht Singh Chandan, Brian H Willis, Krishnarajah Nirantharakumar, Kesvapilla Subramonian

Abstract read
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In one paragraph

Article in Urolithiasis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Urolithiasis in patients with cancer.Nature reviews. Urology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ankush MittalInstitute of Applied Health Research, University of Birmingham, Birmingham, B15 2TT, UK.
Motaz Elmahdy HassanDepartment of Urology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2TH, UK.
Joht Singh ChandanInstitute of Applied Health Research, University of Birmingham, Birmingham, B15 2TT, UK.ORCID http://orcid.org/0000-0002-9561-5141
Brian H WillisInstitute of Applied Health Research, University of Birmingham, Birmingham, B15 2TT, UK.
Krishnarajah NirantharakumarInstitute of Applied Health Research, University of Birmingham, Birmingham, B15 2TT, UK. k.nirantharan@bham.ac.uk.
Kesvapilla SubramonianDepartment of Urology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2TH, UK.
University of Birmingham · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

Medical Research Council G0701649Medical Research Council MR/N007999/1
6 · The paper itself

Abstract

purposeUrolithiasis is a common condition that poses significant morbidity to patients. There are similarities in the development of certain cancers and urinary tract calculi (UTC), however, little is known about their temporal relationship. This study aims to identify if cancer is a risk factor for the development of UTC.

methodsA population-based retrospective cohort study was conducted for the period 1st January 1990 to 1st May 2016. 124,901 exposed patients identified using clinical codes with newly diagnosed cancer were matched to 476,203 unexposed controls by age, gender, BMI, and general practice. The main outcome measure was the risk of developing UTC described by hazard ratios.

resultsThere were 512 incident UTC events in the cancer group compared to 1787 in the unexposed controls. This translated to an adjusted hazard ratio of 1.26 (95% CI 1.14-1.39; p < 0.001). A sub-analysis assessing cancer-specific effects demonstrated increased risks for 10 out of 12 common cancers, most significantly in bladder, colorectal and prostate cancer.

conclusionThis study demonstrated a 26% increased risk of UTC in cancer patients suggesting wider recognition of this risk amongst clinicians could improve diagnosis and prevention of UTC, as well as encourage further research exploring this association.

Indexed as

AdultAgedCohort StudiesFemaleHumansMaleMiddle AgedNeoplasmsRetrospective StudiesRisk AssessmentRisk FactorsUrinary CalculiCalculusCancerCohortRiskStoneUrinaryUrolithiasis

Identifiers

PMID30879105
OpenAlexW2921847574

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.