Evidence map›Paper›PMID 30879064›Full record

ArticleInternational journal of epidemiology2019

Are cannabis users less likely to gain weight? Results from a national 3-year prospective study.

Omayma Alshaarawy, James C Anthony

Abstract read
In one paragraph

Article in International journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. Relationship Between Recreational Cannabis Use andCannabis and cannabinoid research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Omayma AlshaarawyDepartment of Family Medicine, Michigan State University, East Lansing, MI, USA.
James C AnthonyDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Drug Dependence Epidemiology and EnviromicsK05DA015799 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2015
$1.4M
Using pre-clinical biomarkers and epidemiological models to assess the effects of cannabinoids on diseaseR00AT009156 · NCCIH · MICHIGAN STATE UNIVERSITY · PI ALSHAARAWY, OMAYMA O · 2018 to 2020
$744k
Using pre-clinical biomarkers and epidemiological models to assess the effects of cannabinoids on diseaseK99AT009156 · NCCIH · MICHIGAN STATE UNIVERSITY · PI ALSHAARAWY, OMAYMA O · 2016 to 2017
$181k
NCCIH NIH HHS K99 AT009156NCCIH NIH HHS R00 AT009156NIDA NIH HHS K05 DA015799NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

backgroundPre-clinical studies indicate increased food intake and weight gain as cannabinoid effects. Cross-sectional epidemiological studies, however, indicate lower prevalence of obesity among cannabis users. Here, we aim to study the weight-gain research question in the prospectively conducted National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

methodsNESARC was designed to produce nationally representative estimates for the US population. Participants (aged 18+) completed computer-assisted personal interviews on cannabis use, body weight and height at Waves 1 (W1, 2001-02) and 2 (W2, 2004-05). General linear modelling yields estimates for change in body mass index (BMI) regressed on cannabis-use status, with covariate adjustment based on a conceptual model for BMI determinants (n = 33 000).

resultsAt W2, 77% of the participants never used cannabis, 18% had discontinued use ('quit'), 3% were initiates and 2% were persistent users. Estimated W1-to-W2 BMI change shows an increase for all subgroups. Compared with never-users (reference), inverse slope estimates and attenuated change (%) in BMI between W1 and W2 are seen for cannabis-use subgroups: quitters [β = -0.81; 95% confidence interval (CI) = -1.01, -0.60], initiates (β = -0.97; 95% CI = -1.36, -0.57) and persistent users (β = -1.26; 95% CI = -1.81, -0.72).

conclusionThis new prospective study builds from anecdotes, pre-clinical studies and cross-sectional evidence on inverse associations linking cannabis use and obesity and shows an inverse cannabis-BMI increase association. Confirmatory studies with rigorous cannabis and BMI assays will be needed.

Indexed as

Weight GainAdultBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMarijuana SmokingMiddle AgedObesityPrevalenceProspective StudiesRegression AnalysisUnited StatesBMICannabisNESARC

Identifiers

PMID30879064
PMCPMC6857742

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.