SynthesisInternational journal of epidemiology2019
Update on the global epidemiology of intussusception: a systematic review of incidence rates, age distributions and case-fatality ratios among children aged <5 years, before the introduction of rotavirus vaccination.
Synthesis in International journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Ultrasound-guided hydrostatic enema reduction for intussusception in children younger than 12 months: a systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- [Epidemiological characteristics of intussusception in children aged 0-3 years in Jiangsu Province from 2018 to 2023].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- A decade after introduction: survey of training and expansion of ultrasound-guided hydrostatic reduction of intussusception in Ethiopia.Emergency radiology · 2026Article
- Diarrhoea events in offspring exposed to tumour necrosis factor inhibitors and rotavirus vaccine: a population-based cohort study.Rheumatology (Oxford, England) · 2026Article
- Clinical profile, management outcomes, and recurrence patterns of pediatric intussusception in a tertiary care center in South India.Pediatric surgery international · 2026Observational
- Evaluation of rotavirus, pneumococcal conjugate and human papillomavirus vaccination in four Pacific island countries: A cost-effectiveness modelling study.PLoS medicine · 2026Article
- Article
- Intestinal invagination caused by circumferential contraction with longitudinal relaxation of the wall.Biomechanics and modeling in mechanobiology · 2025Article
- Scoring system to predict the failure of hydrostatic reduction for children with intussusception: a single center study.BMC pediatrics · 2025Article
- Current Landscape of Children's Surgery in Africa: A Multicenter Analysis of 16,000 Cases.World journal of surgery · 2025Article
- Case report of a rare variant of adult intussusception with delayed presentation: idiopathic ileocecal colic intussusception.Annals of medicine and surgery (2012) · 2025Article
- Determinants of intussusception in children under five years old visiting paediatric ward in selected hospitals of Sidama region Ethiopia.Scientific reports · 2025Article
- Cost-effectiveness and benefit-risk of rotavirus vaccination in Afghanistan: a modelling analysis informed by post-licensure surveillance.BMC health services research · 2025Article
- Immunoinformatics-driven design of a multi-epitope vaccine targeting neonatal rotavirus with focus on outer capsid proteins VP4 and VP7 and non structural proteins NSP2 and NSP5.Scientific reports · 2025Article
- ASSESSING CATASTROPHIC HEALTHCARE EXPENDITURES IN THE EMERGENCY SURGICAL CARE OF CHILDREN WITH INTUSSUSCEPTION: INSIGHTS FROM A TERTIARY HOSPITAL IN NIGERIA.Annals of Ibadan postgraduate medicine · 2024Article
- The Lack of an Association of Breastfeeding with the Development of Childhood Intussusception: A Nationwide Birth Cohort Survey in Japan.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2024Article
- The Apparent Lack of the Risk of Intussusception Immediately After Rotavirus Vaccination Among Japanese Infants.Viruses · 2024Article
- Infectious etiology of intussusception in Indian children less than 2 years old: a matched case-control analysis.Gut pathogens · 2024Article
- Rotavirus vaccination is a protective factor for adverse outcomes in primary intussusception: a single-center retrospective study.Translational pediatrics · 2024Article
- Geospatial methodology for determining the regional prevalence of hospital-reported childhood intussusception in patients from India.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn some countries that have introduced oral rotavirus vaccines, a small but elevated risk of intussusception-a rare bowel disorder-has been reported. Updated estimates on the global epidemiology of intussusception are needed to help predict the potential number of intussusception cases that could be caused by the vaccine in different settings.
methodsWe estimated incidence rates, age distributions and case-fatality ratios (CFRs) for intussusception hospital admissions among children aged <5 years, before the introduction of rotavirus vaccines. We included all articles identified in a systematic review between January 2002 and January 2018, and contacted authors for more granular unpublished data on age distributions.
resultsWe identified 128 articles containing 227 country datasets (61 age distributions, 71 incidence rates and 95 CFRs). The median age of intussusception ranged from 29 weeks in Africa (83% of cases in the first year of life) to 70 weeks in the Western Pacific region (35% of cases in the first year of life). The median (range) annual incidence of intussusception hospital admissions per 100 000 aged <1 year ranged from 34 (13-56) in Africa to 90 (9-380) in the Western Pacific region. We found extreme differences between the CFRs in Africa (1 death in every 10 hospital admissions) and the rest of the world (fewer than 1 death in every 100-2000 hospital admissions).
conclusionIntussusception epidemiology varies by country and region. Understanding and recognizing these differences will be important when assessing the potential number of intussusception cases associated with rotavirus vaccines.
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