Evidence map›Paper›PMID 30878992›Full record

ArticleBMJ open2019

Effectiveness of complex multiple-risk lifestyle interventions in reducing symptoms of depression: a study protocol for a systematic review and meta-analysis of randomised controlled trials.

Irene Gómez-Gómez, Emma Motrico, Patricia Moreno-Peral, Alina Rigabert, Sonia Conejo-Cerón, Manuel Ortega-Calvo, José-Ignacio Recio, Juan A Bellón

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irene Gómez-GómezDepartment of Psychology, Universidad Loyola Andalucia, Seville, Spain.ORCID 0000-0001-8014-6955
Emma MotricoDepartment of Psychology, Universidad Loyola Andalucia, Seville, Spain.
Patricia Moreno-PeralPrevention and Health Promotion Research Network (redIAPP), ISCIII, Barcelona, Spain.
Alina RigabertDepartment of Psychology, Universidad Loyola Andalucia, Seville, Spain.ORCID 0000-0003-2121-7623
Sonia Conejo-CerónPrevention and Health Promotion Research Network (redIAPP), ISCIII, Barcelona, Spain.
Manuel Ortega-CalvoCentro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain.
José-Ignacio RecioPrevention and Health Promotion Research Network (redIAPP), ISCIII, Barcelona, Spain.
Juan A BellónPrevention and Health Promotion Research Network (redIAPP), ISCIII, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMany studies have explored the impact of lifestyle interventions on depression. However, little is known about the effectiveness of complex multiple-risk lifestyle interventions in reducing symptoms of depression. Our objective is to assess the effectiveness of complex multiple-risk lifestyle interventions in reducing depressive symptoms in the adult population by the acquisition of at least two healthy habits-healthy diet, physical activity and/or smoking cessation. For such purpose, a systematic review and meta-analysis of randomised controlled trials will be conducted. METHOD AND ANALYSIS: MEDLINE (through Ovid and PubMed), Scopus, Cochrane Central Register of Controlled Trials, Web of Science, PsycINFO, OpenGrey Register (System for Information on Grey Literature in Europe) and the International Clinical Trials Registry Platform will be searched for relevant articles. Additionally, a supplementary manual search will be performed using lists of references, references to expert authors and other systematic reviews and/or meta-analyses. Study selection, data extraction (target habits, country, target populations, conditions and statistical data to name a few) and assessment of the risk of bias will be performed separately by two independent researchers. The primary outcome measure will be the reduction of depression symptoms, as measured by validated instruments. We will calculate pooled standardised mean differences and 95% CIs using random-effect models. Heterogeneity, sensitivity and publication bias will be assessed, and sub-group analysis will be performed. Heterogeneity will be explored by random-effects meta-regression analysis. ETHICS AND DISSEMINATION: Ethical approval is not required for this study. The results of this systematic review and meta-analysis will be presented in relevant conferences and published in a peer-review journal. The findings of this study could have important clinical and scientific implications for the improvement of symptoms of depression. PROSPERO REGISTRATION NUMBER: CRD42018100253; Pre-results.

Indexed as

DepressionRisk Reduction BehaviorCognitive Behavioral TherapyHumansMeta-Analysis as TopicRandomized Controlled Trials as TopicSystematic Reviews as TopicTreatment Outcomecomplex multiple-risk interventiondepressionlifestylesmeta-analysisprotocol studysystematic review

Identifiers

PMID30878992
PMCPMC6429884

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.