Evidence map›Paper›PMID 30878984›Full record

ArticleBMJ open2019

Association between caesarean section delivery and obesity in childhood: a longitudinal cohort study in Ireland.

Gwinyai Masukume, Fergus P McCarthy, Philip N Baker, Louise C Kenny, Susan Mb Morton, Deirdre M Murray, Jonathan O'B Hourihane, Ali S Khashan

Abstract readComparative Study
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Association of Cesarean Birth with Body Mass Index Trajectories in Adolescence.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gwinyai MasukumeThe Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland.ORCID 0000-0002-9251-0264
Fergus P McCarthyThe Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland.
Philip N BakerCollege of Life Sciences, University of Leicester, Leicester, United Kingdom.
Louise C KennyDepartment of Women's and Children's Health, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.
Susan Mb MortonCentre for Longitudinal Research - He Ara ki Mua, University of Auckland, Auckland, New Zealand.
Deirdre M MurrayThe Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland.
Jonathan O'B HourihaneThe Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland.
Ali S KhashanThe Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the association between caesarean section (CS) birth and body fat percentage (BF%), body mass index (BMI) and being overweight or obese in early childhood.

designProspective longitudinal cohort study.

settingBabies After Screening for Pregnancy Endpoints: Evaluating the Longitudinal Impact on Neurological and Nutritional Endpoints cohort.

participantsInfants born to mothers recruited from the Screening for Pregnancy Endpoints study, Cork University Maternity Hospital between November 2007 and February 2011. OUTCOME MEASURE: Overweight or obese defined according to the International Obesity Task Force criteria.

resultsOf the 1305 infants, 362 (27.8%) were delivered by CS. On regression analysis, BF% at 2 months did not differ significantly by delivery mode. Infants born by CS had a higher mean BMI at 6 months compared with those born vaginally (adjusted mean difference=0.24; 95% CI 0.06 to 0.41, p value=0.009). At 2 years, no difference was seen across the exposure groups in the risk of being overweight or obese. At 5 years, the association between prelabour CS and the risk of overweight or obesity was not statistically significant (adjusted relative risk ratio, aRRR=1.37; 95% CI 0.69 to 2.69) and the association remained statistically nonsignificant when children who were macrosomic at birth were excluded from the model (aRRR=0.86; 95% CI 0.36 to 2.08).

conclusionAt 6 months of age, children born by CS had a significantly higher BMI but this did not persist into future childhood. There was no evidence to support an association between mode of delivery and long-term risk of obesity in the child.

Indexed as

Birth WeightBody Mass IndexCesarean SectionChildChild, PreschoolCohort StudiesDelivery, ObstetricHumansInfantIrelandLongitudinal StudiesMalePediatric ObesityProspective StudiesRisk Factorsbody compositionbody fatcaesarean sectionchildhoodIrelandobesity

Identifiers

PMID30878984
PMCPMC6429933

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.