Trial reportGait & posture2019
The contralateral knee may not be a valid control for biomechanical outcomes after unilateral total knee arthroplasty.
Trial report in Gait & posture, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- There is more to the knee joint than just the quadriceps: A systematic review with meta-analysis and evidence gap map of hamstring strength, flexibility, and morphology in individuals with gradual-onset knee disorders.Journal of sport and health science · 2024Pooled it
- Distal femoral morphology as a risk factor for osteoarthritis.Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- Intentional asymmetric balancing in robotic-assisted valgus TKA: Early outcomes and intraoperative laxity changes.Journal of experimental orthopaedics · 2026Article
- Preoperative and Post-Rehabilitation Predictors of Gait Biomechanics Six Months After Total Knee Arthroplasty.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Proteomics Reveals Increased Periostin in Synovial Fluid From Canine and Human Anterior Cruciate Ligament Injury.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Foot progression angle asymmetry as a potential biomechanical marker of radiographic severity in knee osteoarthritis.Frontiers in bioengineering and biotechnology · 2025Article
- Evaluation of the effects of cementless total hip replacement on femoral length in skeletally immature dogs.Veterinary surgery : VS · 2025Article
- [Blood flow restriction training (BFRT) in patients before and after total knee arthroplasty].Orthopadie (Heidelberg, Germany) · 2024Article
- Investigation of Biomechanical Differences in Level Walking between Patients with Bilateral and Unilateral Total Knee Replacements.Bioengineering (Basel, Switzerland) · 2024Article
- Asymmetric gap balancing improves knee kinematic following primary total knee arthroplasty.Arthroplasty (London, England) · 2024Article
- Gait symmetry - A valid parameter for pre and post planning for total knee arthroplasty.Journal of musculoskeletal & neuronal interactions · 2022Article
- Knee biomechanics and contralateral knee osteoarthritis progression after total knee arthroplasty.Gait & posture · 2022Article
- [Development of on-line lateral stiffness measurement system for anterior cruciate ligament and its influence on anterior cruciate ligament reconstruction].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021Article
- Does contralateral knee range of motion predict postoperative knee range of motion after total knee arthroplasty?Knee surgery & related research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundAlthough unilateral symptoms and unilateral total knee arthroplasty (TKA) are common, many patients have bilateral radiographic osteoarthritis (OA). Because the contralateral (non-operated) limb is often used as a comparison for clinical and biomechanical outcomes, it is important to know if the presence of OA influences movement patterns in either limb. RESEARCH QUESTION: The purpose of this study was to compare bilateral sagittal plane biomechanics between subjects with and without contralateral knee OA after unilateral TKA.
methodsFifty-three subjects who underwent unilateral TKA underwent three-dimensional gait analysis 6-24 months after surgery participated in this cross-sectional study. Kellgren-Lawrence (KL) OA severity in the contralateral limb was measured, and subjects were classified into either a non-OA (KL 0 or 1) or OA (KL 2-4) group. Mixed-model ANOVA tests with factors of group and limb were used to compare biomechanical measures. In the presence of a significant interaction effect, post-hoc comparisons were performed.
resultsThe OA group had more knee flexion at initial contact, less knee flexion and extension excursions, and less knee extension in the contralateral limb compared to the non-OA group. The non-OA group had significant differences between limbs, with more knee flexion at initial contact, less knee joint excursion, and less peak knee extension on the operated limb compared to the contralateral limb, whereas there were no limb differences for the OA group. Kinetic variables were not different in the ANOVA models. SIGNIFICANCE AND
interpretationSubjects with contralateral knee OA have more symmetrical gait, although they adopt a more abnormal and stiff-legged gait pattern bilaterally. Researchers and clinicians should consider radiographic disease severity, not just symptoms, in the contralateral limb when identifying appropriate subject samples for unilateral biomechanical studies. Symmetrical movement patterns between limbs after surgery should not be the sole factor upon which movement recovery is based.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.