Evidence map›Paper›PMID 30877715›Full record

Observational studyDiabetes & metabolism journal2019

Presence of Carotid Plaque Is Associated with Rapid Renal Function Decline in Patients with Type 2 Diabetes Mellitus and Normal Renal Function.

Da Hea Seo, So Hun Kim, Joon Ho Song, Seongbin Hong, Young Ju Suh, Seong Hee Ahn, Jeong Taek Woo, Sei Hyun Baik, Yongsoo Park, Kwan Woo Lee and 3 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Diabetes & metabolism journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Da Hea Seo *Department of Endocrinology and Metabolism, Inha University School of Medicine, Incheon, Korea.ORCID 0000-0003-2767-0293
So Hun Kim *Department of Endocrinology and Metabolism, Inha University School of Medicine, Incheon, Korea.ORCID 0000-0002-2554-3664
Joon Ho SongDepartment of Nephrology and Hypertension, Inha University School of Medicine, Incheon, Korea.
Seongbin HongDepartment of Endocrinology and Metabolism, Inha University School of Medicine, Incheon, Korea.
Young Ju SuhDepartment of Biomedical Sciences, Inha University School of Medicine, Incheon, Korea.
Seong Hee AhnDepartment of Endocrinology and Metabolism, Inha University School of Medicine, Incheon, Korea.
Jeong Taek WooDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Sei Hyun BaikDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Yongsoo ParkDepartment of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, IL, USA.
Kwan Woo LeeDepartment of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.
Young Seol KimDepartment of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.
Moonsuk NamDepartment of Endocrinology and Metabolism, Inha University School of Medicine, Incheon, Korea. namms@inha.ac.kr.ORCID 0000-0003-1756-8498
KNDP Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent evidences indicate that early rapid renal function decline is closely associated with the development and progression of diabetic kidney disease. We have investigated the association between carotid atherosclerosis and rapid renal function decline in patients with type 2 diabetes mellitus and preserved renal function.

methodsIn a prospective, multicenter cohort, a total of 967 patients with type 2 diabetes mellitus and preserved renal function were followed for 6 years with serial estimated glomerular filtration rate (eGFR) measurements. Common carotid intima-media thickness (CIMT) and presence of carotid plaque were assessed at baseline. Rapid renal function decline was defined as an eGFR decline >3.3% per year.

resultsOver a median follow-up of 6 years, 158 participants (16.3%) developed rapid renal function decline. While there was no difference in CIMT, the presence of carotid plaque in rapid decliners was significantly higher than in non-decliners (23.2% vs. 12.2%,

conclusionClose monitoring of renal function and early intensive management may be beneficial in patients with type 2 diabetes mellitus and carotid plaques.

Indexed as

AdultAgedBiomarkersCarotid Intima-Media ThicknessCarotid StenosisDiabetes Mellitus, Type 2Diabetic NephropathiesDisease ProgressionFemaleFollow-Up StudiesGlomerular Filtration RateHumansMaleMiddle AgedPlaque, AtheroscleroticPrognosisBiomarkersCarotid stenosisDiabetes mellitus, type 2Diabetic nephropathies

Identifiers

PMID30877715
PMCPMC6943261

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.