Evidence map›Paper›PMID 30877605›Full record

ArticleNeuroinformatics2019

Fast and Precise Hippocampus Segmentation Through Deep Convolutional Neural Network Ensembles and Transfer Learning.

Dimitrios Ataloglou, Anastasios Dimou, Dimitrios Zarpalas, Petros Daras

Abstract read
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In one paragraph

Article in Neuroinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dimitrios AtaloglouInformation Technologies Institute (ITI), Centre for Research and Technology HELLAS, 1st km Thermi - Panorama, 57001, Thessaloniki, Greece. ataloglou@iti.gr.ORCID 0000-0001-8050-0643
Anastasios DimouInformation Technologies Institute (ITI), Centre for Research and Technology HELLAS, 1st km Thermi - Panorama, 57001, Thessaloniki, Greece.
Dimitrios ZarpalasInformation Technologies Institute (ITI), Centre for Research and Technology HELLAS, 1st km Thermi - Panorama, 57001, Thessaloniki, Greece.
Petros DarasInformation Technologies Institute (ITI), Centre for Research and Technology HELLAS, 1st km Thermi - Panorama, 57001, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Automatic segmentation of the hippocampus from 3D magnetic resonance imaging mostly relied on multi-atlas registration methods. In this work, we exploit recent advances in deep learning to design and implement a fully automatic segmentation method, offering both superior accuracy and fast result. The proposed method is based on deep Convolutional Neural Networks (CNNs) and incorporates distinct segmentation and error correction steps. Segmentation masks are produced by an ensemble of three independent models, operating with orthogonal slices of the input volume, while erroneous labels are subsequently corrected by a combination of Replace and Refine networks. We explore different training approaches and demonstrate how, in CNN-based segmentation, multiple datasets can be effectively combined through transfer learning techniques, allowing for improved segmentation quality. The proposed method was evaluated using two different public datasets and compared favorably to existing methodologies. In the EADC-ADNI HarP dataset, the correspondence between the method's output and the available ground truth manual tracings yielded a mean Dice value of 0.9015, while the required segmentation time for an entire MRI volume was 14.8 seconds. In the MICCAI dataset, the mean Dice value increased to 0.8835 through transfer learning from the larger EADC-ADNI HarP dataset.

Indexed as

Deep LearningNeural Networks, ComputerAgedAged, 80 and overDatabases, FactualFemaleHippocampusHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMachine LearningMagnetic Resonance ImagingMaleMiddle AgedReproducibility of ResultsTime FactorsConvolutional neural networksDeep learningError correctionHippocampus segmentationMagnetic resonance imagingTransfer learning

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.