Evidence map›Paper›PMID 30877579›Full record

ArticleAIDS and behavior2019

Depression Symptom Trajectories Among Mothers Living with HIV in Rural Uganda.

Itziar Familiar, Alla Sikorskii, Sarah Murray, Horacio Ruisenor-Escudero, Noeline Nakasujja, Clinton Korneffel, Michael Boivin, Judith Bass

Abstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Itziar FamiliarDepartment of Psychiatry, Michigan State University, 909 Fee Rd. A322, East Lansing, MI, USA. familiar@msu.edu.
Alla SikorskiiDepartments of Psychiatry and Statistics, Michigan State University, East Lansing, MI, USA.
Sarah MurrayMental Health Department, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Horacio Ruisenor-EscuderoDepartment of Psychiatry, Michigan State University, 909 Fee Rd. A322, East Lansing, MI, USA.
Noeline NakasujjaDepartment of Psychiatry, College of Health Sciences, Makerere University, Kampala, Uganda.
Clinton KorneffelCollege of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA.
Michael BoivinDepartments of Psychiatry and Neurology, Michigan State University, East Lansing, MI, USA.
Judith BassDepartments of Psychiatry and Statistics, Michigan State University, East Lansing, MI, USA.

Funding

Global Mental Health Training ProgramT32MH103210 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Judith Karen Bass, Sarah Sutherlin-McIvor Murray · 2015 to 2026
$4.0M
Enhancing Ugandan HIV-Affected Child Development with Caregiver TrainingR01HD070723 · NICHD · MICHIGAN STATE UNIVERSITY · PI BASS, JUDITH KAREN, BOIVIN, MICHAEL JOSEPH · 2011 to 2015
$2.8M
NICHD NIH HHS R01 HD070723NIMH NIH HHS T32MH10321NIMH NIH HHS T32 MH103210
6 · The paper itself

Abstract

The aim was to identify latent class trajectories of depression symptoms among HIV+ women in Uganda. Depression was assessed at four time points using the Hopkins Symptom Checklist among 288 women caring for a child 2-5 years old. Mixture modeling was used to estimate the number and nature of classes defined by trajectories of depressive symptoms over time. Maternal and child characteristics were explored as predictors of class. Three trajectories of symptoms of depression were identified; (1) stable-low, (2) moderate-subclinical, and (3) chronic-high. About 8% of women reported moderately or highly elevated symptoms at the first assessment and consistently onward (i.e. chronically). Higher anxiety levels, less social support, more functionality problems, and more executive behavior problems in children predicted membership in the moderate-subclinical and chronic-high classes. Identifying patterns of depression trajectories can help target intervention efforts for women who are likely to experience the most chronic and impairing symptomatology.

Indexed as

AdolescentAdultAnxietyChild, PreschoolDepressionDepressive DisorderExecutive FunctionFemaleHIV InfectionsHumansMiddle AgedMothersProblem BehaviorRural PopulationSocial SupportUgandaDepressionHIVLatent trajectoryLow- and middle-income countries (LMIC)Women

Identifiers

PMID30877579
PMCPMC6745285

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.