Evidence map›Paper›PMID 30877464›Full record

ArticleEuropean radiology2019

Predicting pathological subtypes and stages of thymic epithelial tumors using DWI: value of combining ADC and texture parameters.

Bo Li, Yong-Kang Xin, Gang Xiao, Gang-Feng Li, Shi-Jun Duan, Yu Han, Xiu-Long Feng, Wei-Qiang Yan, Wei-Cheng Rong, Shu-Mei Wang and 2 more

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  6. Diagnostic value of apparent diffusion coefficient in predicting pathological T stage in patients with thymic epithelial tumor.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Bo LiDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Yong-Kang XinDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Gang XiaoDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Gang-Feng LiDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Shi-Jun DuanDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Yu HanDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Xiu-Long FengDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Wei-Qiang YanDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Wei-Cheng RongDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Shu-Mei WangDepartment of Pathology, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China.
Yu-Chuan HuDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China. hyc3140@126.com.
Guang-Bin CuiDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Military Medical University of PLA Airforce (Fourth Military Medical University), Xi'an, 710038, Shaanxi, People's Republic of China. cgbtd@126.com.

Funding

the Science and Technology Innovation Development Foundation of Tangdu Hospital 2017LCYJ004
6 · The paper itself

Abstract

objectivesTo explore the value of combining apparent diffusion coefficients (ADC) and texture parameters from diffusion-weighted imaging (DWI) in predicting the pathological subtypes and stages of thymic epithelial tumors (TETs).

methodsFifty-seven patients with TETs confirmed by pathological analysis were retrospectively enrolled. ADC values and optimal texture feature parameters were compared for differences among low-risk thymoma (LRT), high-risk thymoma (HRT), and thymic carcinoma (TC) by one-way ANOVA, and between early and advanced stages of TETs were tested using the independent samples t test. Receiver operating characteristic (ROC) curve analysis was performed to determine the differentiating efficacy.

resultsThe ADC values in LRT and HRT were significantly higher than the values in TC (p = 0.004 and 0.001, respectively), also in early stage, values were significantly higher than ones in advanced stage of TETs (p < 0.001). Among all texture parameters analyzed in order to differentiate LRT from HRT and TC, the V

conclusionsCombination of ADC and DWI texture parameters improved the differentiating ability of TET grades, which could potentially be useful in clinical practice regarding the TET evaluation before treatment. KEY POINTS: • DWI texture analysis is useful in differentiating TET subtypes and stages. • Combination of ADC and DWI texture parameters may improve the differentiating ability of TET grades. • DWI texture analysis could potentially be useful in clinical practice regarding the TET evaluation before treatment.

Indexed as

AdenocarcinomaCarcinoma, Squamous CellDiffusion Magnetic Resonance ImagingFemaleHumansMaleMiddle AgedNeoplasms, Glandular and EpithelialNeuroendocrine TumorsRetrospective StudiesROC CurveThymomaThymus NeoplasmsDiffusion magnetic resonance imagingNeoplasm stagingTexture analysisThymic epithelial tumors

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.