ArticleEuropean radiology2019
Early detection with MRI of incomplete treatment of spine metastases after percutaneous cryoablation.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Percutaneous cryoablation in the management of spinal metastases: a comprehensive systematic review and meta-analysis.Journal of neuro-oncology · 2025Pooled it
- Applications of spectral CT calcium suppression for percutaneous bone tumor ablation procedures.Radiology case reports · 2025Article
- Interventional Radiology Management of Bone Metastasis Pain: Strategies and Techniques.Cardiovascular and interventional radiology · 2025Review
- Review
- Review
- The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors.Current oncology (Toronto, Ont.) · 2023Review
- CIRSE Standards of Practice on Thermal Ablation of Bone Tumours.Cardiovascular and interventional radiology · 2022Article
- Anterior epidural carbon dioxide dissection during spine cryoablation.Japanese journal of radiology · 2022Article
- Incidence of patients with bone metastases at diagnosis of solid tumors in adults: a large population-based study.Annals of translational medicine · 2020Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate post-ablation MRI for the detection of incompletely treated spinal osseous metastases (SOM) after cryoablation and to propose a post-ablation imaging classification.
methodsAfter IRB consent, all patients treated with cryoablation of SOM between 2011 and 2017 having at least 1-year minimum follow-up and a spine MRI within 4 months after cryoablation were retrospectively included. A classification of MRI images into four types was set up. The primary endpoint of our study was to assess the diagnostic performance of the post-ablation MRI. The secondary endpoints were the 1-year complete treatment rate (CTR) and complications.
resultsFifty-four SOMs in 39 patients were evaluated. Post-ablation MRI was performed with a median delay of 25 days after cryoablation. Images were evaluated by two independent readers according to the pre-established image classification. Sensitivity and specificity for the detection of residual tumor were 77.3% (95%CI = 62.2-88.5) and 85.9% (95%CI = 75.0-93.4), respectively. Types I, II, III, and IV of the classification were associated with a 1-year complete treatment in 100%, 83.3%, 35.7%, and 10% of cases, respectively. The 1-year CTR was 59.3% for all 54 metastases, and 95.8% for metastases measuring less than 25 mm and at least 2 mm or more away from the spinal canal. Two grade 3 and two grade 2 adverse events according to the CTCAE were reported.
conclusionsMRI after cryoablation is useful for the evaluation of the ablation efficacy. The classification of post-cryoablation MRI provides reliable clues for the prediction of complete treatment at 1 year. KEY POINTS: • MRI performed 25 days after cryoablation is useful to evaluate the efficacy. • The proposed classification provides a reliable clue for complete cryoablation. • Percutaneous cryoablation of spinal metastases is highly effective for lesions less than 25 mm in diameter and of at least 2 mm away from the spinal canal.
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