Evidence map›Paper›PMID 30877412›Full record

ReviewClinical and translational medicine2019

Cell membrane protein functionalization of nanoparticles as a new tumor-targeting strategy.

Anna Pasto, Federica Giordano, Michael Evangelopoulos, Alberto Amadori, Ennio Tasciotti

Abstract readReview
In one paragraph

Review in Clinical and translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Nanomedicine in Bladder Cancer Therapy.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Stem Cell Mimicking Nanoencapsulation for Targeting Arthritis.International journal of nanomedicine · 2021
    Review
  15. Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems.Frontiers in bioengineering and biotechnology · 2021
    Review
  16. Review
  17. Article
  18. Review
  19. Cell Membrane Coated-Biomimetic Nanoplatforms Toward Cancer Theranostics.Frontiers in bioengineering and biotechnology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna PastoVeneto Institute of Oncology-IRCCS, Padua, Italy.ORCID http://orcid.org/0000-0002-5783-0668
Federica GiordanoSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Michael EvangelopoulosCenter for Biomimetic Medicine, Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA.
Alberto AmadoriVeneto Institute of Oncology-IRCCS, Padua, Italy.
Ennio TasciottiCenter for Biomimetic Medicine, Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA. etasciotti@houstonmethodist.org.

Funding

Biomimetic nanovesicles to overcome multiple physiological barriers for primary and metastatic triple negative breast cancer therapyR56CA213859 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI CHANG, JENNY C-N · 2017 to 2017
$300k
Cancer Prevention and Research Institute of Texas RP170466Cancer Prevention and Research Institute of Texas RP180394National Cancer Institute 1R56CA213859
6 · The paper itself

Abstract

Nanoparticles have seen considerable popularity as effective tools for drug delivery. However, non-specific targeting continues to remain a challenge. Recently, biomimetic nanoparticles have emerged as an innovative solution that exploits biologically-derived components to improve therapeutic potential. Specifically, cell membrane proteins extracted from various cells (i.e., leukocytes, erythrocytes, platelets, mesenchymal stem cells, cancer) have shown considerable promise in bestowing nanoparticles with increased circulation and targeting efficacy. Traditional nanoparticles can be detected and removed by the immune system which significantly hinders their clinical success. Biomimicry has been proposed as a promising approach to overcome these limitations. In this review, we highlight the current trends in biomimetic nanoparticles and describe how they are being used to increase their chemotherapeutic effect in cancer treatment.

Indexed as

BioinspiredBiomimicryCancerDrug deliveryNanoparticles

Identifiers

PMID30877412
PMCPMC6420595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.