Evidence map›Paper›PMID 30877359›Full record

SynthesisWorld journal of urology2019

Redo-urethroplasty for the management of recurrent urethral strictures in males: a systematic review.

Sara Jasionowska, Oliver Brunckhorst, Rowland W Rees, Asif Muneer, Kamran Ahmed

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Advances in Urogenital Trauma and Reconstruction.BioMed research international · 2020
    Article
  9. Article
  10. Analysis of the Determinants, Characteristics and Management of Recurrent Urethral Strictures.Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Sara JasionowskaMRC Centre for Transplantation, Guy's Hospital, King's College London, London, UK.
Oliver BrunckhorstMRC Centre for Transplantation, Guy's Hospital, King's College London, London, UK.
Rowland W ReesUrology Department, University Hospital Southampton, NHS Foundation Trust, Southampton, UK.
Asif MuneerDepartment of Urology, NIHR Biomedical Research Centre, University College Hospital, University College London Hospitals NHS Foundation Trust, London, UK.
Kamran AhmedMRC Centre for Transplantation, Guy's Hospital, King's College London, London, UK. kamran.ahmed@kcl.ac.uk.
King's College Hospital · GBKing's College London · GBUCL Biomedical Research Centre · GBUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRedo-urethroplasty is a challenge for any genitourethral surgeon, with a number of techniques previously described. This systematic review aims to identify the surgical techniques described in the literature and evaluate the evidence for their effectiveness in managing recurrent urethral strictures. MATERIALS AND

methodsA systematic review of the MEDLINE and EMBASE databases from 1945 to July 2018 was performed and the urethroplasty procedures were classified according to the site and surgical technique. Primary outcomes included success rates measured via re-stricture rates and the post-op maximum urinary flow rate. Secondary outcomes included complication rates and patient-reported quality of life.

resultsA total of 39 identified studies met the inclusion criteria. Twenty-two studies described the use of excision and primary anastomotic urethroplasty with success rates showing wide variability (58-100%). Success rates reported according to the site of the stricture also varied: bulbar (58-100%) and posterior (69-100%) recurrent strictures. One-stage substitution urethroplasty was described in 25 studies with success rates of 18-100%, with the best outcomes reported for bulbar (58-100%) and hypospadias-related (78.6-82%) strictures. Two-stage substitution urethroplasty was described in 12 studies with the success rates of 20-100%, with the best evidence related to hypospadias-related and posterior urethral strictures. The buccal mucosa graft was the graft source with the best evidence for substitution urethroplasty (18-100%).

conclusionsTrends of effectiveness were identified for redo-urethroplasty modalities in different locations. However, the current levels of evidence are limited to small observational studies, highlighting the need for further larger prospective data to evaluate different techniques used for recurrent urethral strictures.

Indexed as

ReoperationDecision TreesHumansMaleRecurrenceUrethraUrethral StrictureUrologic Surgical Procedures, MaleFailed urethroplastyRedo-urethroplastyRepeat urethroplastyUrethral stricture

Identifiers

PMID30877359
PMCPMC6717180
OpenAlexW2921039266

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.