Evidence map›Paper›PMID 30877269›Full record

Trial reportTranslational psychiatry2019

Endogenous dopamine release under transcranial direct-current stimulation governs enhanced attention: a study with positron emission tomography.

Mina Fukai, Tomoyasu Bunai, Tetsu Hirosawa, Mitsuru Kikuchi, Shigeru Ito, Yoshio Minabe, Yasuomi Ouchi

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Translational psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04964427 (The Effects of Methylphenidate), which is not on this map. Cited by 55 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 5 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04964427 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effects of Methylphenidate (MPH) and Non-invasive Brain Stimulation (tDCS) on Inhibitory Control Children With Attention-Deficit/Hyperactivity Disorder (ADHD)

TypeinterventionalSponsorBambino Gesù Hospital and Research InstituteRan2021 to 2022Enrolled26ConditionsAttention Deficit Hyperactivity DisorderArmsMethylphenidate, anodal tDCS, sham tDCS
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 5 syntheses or guidelines pooled it, 104 citations in OpenAlex.

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  12. Neurotransmitter Systems in Alzheimer's Disease.Current issues in molecular biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mina FukaiDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Tomoyasu BunaiDepartment of Biofunctional Imaging, Preeminent Medical Photonics Education and Research Center, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Tetsu HirosawaDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Mitsuru KikuchiDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Shigeru ItoGlobal Strategic Challenge Center, Hamamatsu Photonics KK, Hamamatsu, Japan.
Yoshio MinabeDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Yasuomi OuchiDepartment of Biofunctional Imaging, Preeminent Medical Photonics Education and Research Center, Hamamatsu University School of Medicine, Hamamatsu, Japan. ouchi@hama-med.ac.jp.
Kanazawa University · JPHamamatsu University School of Medicine · JPHamamatsu Photonics (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial direct-current stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC) has been established as an effective and noninvasive method to modulate cognitive function. Nevertheless, the mechanisms causing those cognitive changes under the tDCS remain largely unknown. We strove to elucidate the cognito-biological relation under the tDCS condition by examining whether the dopamine system activated by tDCS is involved in cognitive changes in human participants, or not. To evaluate the dopamine system, we used [

Indexed as

AttentionTranscranial Direct Current StimulationAdultCross-Over StudiesDopamineDopamine AntagonistsDouble-Blind MethodHealthy VolunteersHumansMaleNeuropsychological TestsPositron-Emission TomographyPrefrontal CortexRacloprideVentral StriatumYoung AdultDopamineDopamine AntagonistsRaclopride

Identifiers

PMID30877269
PMCPMC6420561
OpenAlexW2922129833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.