Evidence map›Paper›PMID 30877049›Full record

Trial reportJournal of the American Academy of Child and Adolescent Psychiatry2020

A Randomized Controlled Trial of Attention Bias Modification Treatment in Youth With Treatment-Resistant Anxiety Disorders.

Jeremy W Pettit, Michele Bechor, Yasmin Rey, Michael W Vasey, Rany Abend, Daniel S Pine, Yair Bar-Haim, James Jaccard, Wendy K Silverman

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Academy of Child and Adolescent Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01819311 (Attention Bias Modification Training for Child Anxiety CBT Nonresponders), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01819311 nacompletednot on this map

Attention Bias Modification Training for Child Anxiety CBT Nonresponders

TypeinterventionalSponsorFlorida International UniversityRan2013 to 2017Enrolled64ConditionsAnxiety DisordersArmsAttention Bias Modification, Placebo Attention Task
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Difficult-to-Treat Anxiety: A Neurocomputational Framework.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
  7. Article
  8. Article
  9. Multiple Adaptive Attention-Bias-Modification Programs to Alter Normative Increase in the Error-Related Negativity in Adolescents.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
  10. Review
  11. Novel mechanism-based treatments for pediatric anxiety and depressive disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Attentional biases in human anxiety.Neuroscience and biobehavioral reviews · 2022
    Review
  17. Article
  18. Implementing Cognitive-Behavioral Therapy in Children and Adolescents with Anxiety Disorders.Klinicheskaia i spetsial'naia psikhologiia = Clinical psychology and special education · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Jeremy W PettitFlorida International University, Miami. Electronic address: jpettit@fiu.edu.
Michele BechorFlorida International University, Miami.
Yasmin ReyFlorida International University, Miami.
Michael W VaseyOhio State University, Columbus.
Rany AbendNational Institute of Mental Health, Bethesda, MD.
Daniel S PineNational Institute of Mental Health, Bethesda, MD.
Yair Bar-HaimTel Aviv University, Israel.
James JaccardNew York University, New York, NY.
Wendy K SilvermanYale University, New Haven CT.
Florida International University · USNational Institute of Mental Health · USNew York University · USTel Aviv University · ILThe Ohio State University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
Attention Bias Modification Training in Child Anxiety CBT NonrespondersR34MH097931 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI PETTIT, JEREMY W, SILVERMAN, WENDY K. · 2013 to 2015
$623k
NCATS NIH HHS UL1 TR001863NIMH NIH HHS R34 MH097931
6 · The paper itself

Abstract

objectiveRandomized clinical trials of augmentation strategies for youth with treatment-resistant anxiety disorders do not exist. This report presents findings from an efficacy trial of attention bias modification treatment (ABMT) as an augment for this population compared with attention control training (ACT).

methodSixty-four youths (34 boys; mean age 11.7 years) who continued to meet for anxiety diagnoses after completing cognitive-behavioral therapy were randomized to ABMT or ACT. ABMT and ACT consisted of dot-probe attention training trials presenting angry and neutral faces; probes appeared in the location of neutral faces on 100% of trials in ABMT and 50% of trials in ACT. Independent evaluators, youths, and parents completed ratings of youth anxiety severity, and youths completed measures of attention bias to threat and attention control at pretreatment, post-treatment, and 2-month follow-up.

resultsThe 2 arms showed significant decreases in anxiety severity, with no differences between arms. Specifically, across informants, anxiety severity was significantly decreased at post-treatment and decreases were maintained at follow-up. Primary anxiety disorder diagnostic recovery combined across arms was 50% at post-treatment and 58% at follow-up. Attention control, but not attention bias to threat, was significantly improved at post-treatment in the 2 arms.

conclusionThis is the first study to show anxiety can be decreased in youth who did not respond to cognitive-behaviorial therapy, and that the anxiety-decreasing effect is found using these 2 attention training contingency schedules. These findings and increases in attention control in the 2 arms raise intriguing questions about mechanisms of decreasing anxiety in treatment-resistant youth with attention training that require further research. CLINICAL TRIAL REGISTRATION INFORMATION: Attention Bias Modification Training for Child Anxiety CBT Nonresponders; https://clinicaltrials.gov/; NCT01819311.

Indexed as

Attentional BiasCognitive Behavioral TherapyAdolescentAnxietyAnxiety DisordersChildFemaleHumansMaleTreatment Outcomeanxietyattention bias modificationchildrentreatment

Identifiers

PMID30877049
PMCPMC6744353
OpenAlexW2920800445

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.