Evidence map›Paper›PMID 30876494›Full record

ArticleGynecologic oncology2019

Validation and application of a module of the MD Anderson Symptom Inventory for measuring perioperative symptom burden in patients with gynecologic cancer (the MDASI-PeriOp-GYN).

Xin Shelley Wang, Qiuling Shi, Loretta A Williams, Charles S Cleeland, Araceli Garcia-Gonzalez, Ting-Yu Chen, Denita R Shahid, Pedro T Ramirez, Maria D Iniesta, Ashley M Siverand and 1 more

Abstract read
In one paragraph

Article in Gynecologic oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  8. Patient-reported symptoms at discharge and risk of complications after gynecologic surgery.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Article
  9. Article
  10. Impact of a tiered discharge opioid algorithm on prescriptions and patient-reported outcomes after open gynecologic surgery.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2021
    Article
  11. Article
  12. Longitudinal patient-reported outcomes and restrictive opioid prescribing after minimally invasive gynecologic surgery.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xin Shelley WangDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America. Electronic address: xswang@mdanderson.org.
Qiuling ShiDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Loretta A WilliamsDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Charles S CleelandDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Araceli Garcia-GonzalezDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Ting-Yu ChenDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Denita R ShahidDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Pedro T RamirezDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Maria D IniestaDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Ashley M SiverandDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Larissa A MeyerDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Improving Recovery after Major Cancer Surgery using Patient-Reported OutcomesR01CA205146 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WANG, XIN SHELLEY · 2016 to 2019
$2.6M
Health Services Career Development: Improving Medical Decisions in Ovarian CancerK07CA201013 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MEYER, LARISSA ALEJANDRA · 2016 to 2020
$853k
NCI NIH HHS K07 CA201013NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA205146
6 · The paper itself

Abstract

objectiveUsing patient-reported outcomes (PROs) in perioperative care is increasingly common. We report the development, validation, and application of an MD Anderson Symptom Inventory version for use in patients undergoing surgery for gynecologic cancer or benign conditions (MDASI-PeriOp-GYN).

methodsOur process included: (1) generating PeriOp-GYN-specific candidate items from qualitative interviews with patients, followed by input from an expert panel; (2) dropping items that lacked independent clinical relevance; (3) validating psychometric properties (reliability, validity) of the resulting MDASI-PeriOp-GYN; and (4) conducting cognitive debriefing interviews with patients to confirm ease of comprehension, relevance, and acceptability.

resultsQualitative interviews with 40 patients generated 9 new PeriOp-GYN symptom items (bloating, abdominal cramping, constipation, hot flashes, dizziness, grogginess/confusion, urinary pain, difficulty urinating, and diarrhea) that, along with the core MDASI items, formed the new MDASI-PeriOp-GYN. A total of 150 patients (minimally invasive surgery (MIS) = 69, open surgery = 81) participated in the validation study; 121 patients also provided retest data. Cronbach alphas were 0.89 for symptoms and 0.86 for interference. Test-retest reliability was 0.88 for all symptom severity items. Known-group validity was supported by the detection of significant differences in symptom and interference levels by performance status (P < 0.01) and for all symptoms by surgery type (P < 0.01). Cognitive debriefing with 20 of the 150 patients demonstrated that the MDASI-PeriOp-GYN is an easy-to-use and understandable tool.

conclusionsThe MDASI-PeriOp-GYN is a valid, reliable, concise tool for measuring symptom severity and functional interference in patients undergoing gynecologic surgery and can be useful in assessing postoperative symptom burden via PROs.

Indexed as

Patient Reported Outcome MeasuresCognition DisordersFemaleGenital Neoplasms, FemaleGynecologic Surgical ProceduresHumansMiddle AgedPerioperative PeriodPsychometricsReproducibility of ResultsSeverity of Illness IndexTumor BurdenAssessmentCancerGynecologicalMDASISymptomsValidation

Identifiers

PMID30876494
PMCPMC6422045
OpenAlexW2917711884

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.