Evidence map›Paper›PMID 30876476›Full record

ArticleAIDS research and therapy2019

HIV late presentation and advanced HIV disease among patients with newly diagnosed HIV/AIDS in Southwestern China: a large-scale cross-sectional study.

Xi Hu, Bingyu Liang, Chongxing Zhou, Junjun Jiang, Jiegang Huang, Chuanyi Ning, Jie Liu, Bo Zhou, Ning Zang, Jinzhen Lai and 9 more

Open access · goldAbstract read
In one paragraph

Article in AIDS research and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Xi HuGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Bingyu LiangGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Chongxing ZhouInstitute of HIV/AIDS Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, 530200, Guangxi, China.
Junjun JiangGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Jiegang HuangGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Chuanyi NingGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Jie LiuGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Bo ZhouGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Ning ZangGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Jinzhen LaiGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Rongfeng ChenGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Yanyan LiaoGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Peijiang PanGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Xin LiuGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Guanghua LanInstitute of HIV/AIDS Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, 530200, Guangxi, China.
Xianwu PangInstitute of HIV/AIDS Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, 530200, Guangxi, China.
Li YeGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China. yeli@gxmu.edu.cn.
Zhiyong ShenInstitute of HIV/AIDS Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, 530200, Guangxi, China. shenzhiyong99999@sina.com.
Hao LiangGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China. lianghao@gxmu.edu.cn.
Guangxi Medical University · CNGuangxi Center for Disease Prevention and Control · CN

Funding

China Postdoctoral Science Foundation 2018M640890China Postdoctoral Science Foundation 2018M643382Guangxi Science Foundation 2018JJA140536Guangxi Science Foundation for Distinguished Young Scholars 2018JJG140004National Natural Science Foundation of China 31860040National Natural Science Foundation of China 81560326National Natural Science Foundation of China 81660334National Natural Science Foundation of China 81803295National Natural Science Foundation of China 81860655Natural Science Foundation of Guangxi Province 2016GXNSFBA380189Natural Science Foundation of Guangxi Province 2018GXNSFAA138002Natural Science Foundation of Guangxi Province 2018GXNSFAA138070Science Foundation for The Excellent Young Scholars of Guangxi Collaborative Innovation Center for Biomedicine GCICB-TC-2017004Science Foundation for The Excellent Young Scholars of Guangxi Collaborative Innovation Center for Biomedicine GCICB-TC-2017015
6 · The paper itself

Abstract

objectiveThis study aimed to investigate the prevalence of HIV late presentation and advanced HIV disease and to identify the factors associated with HIV late presentation and advanced HIV disease among patients with newly diagnosed HIV/AIDS in the Guangxi Zhuang Autonomous Region, in Southwestern China.

methodsPatients with newly diagnosed HIV registered in the HIV surveillance system of Guangxi Centers for Disease Control between January 2012 and December 2016 were included in this study.

resultsOf 45,118 newly diagnosed patients, 70.2% had late presentation, and 45.1% had advanced HIV disease. A higher prevalence of late presentation and advanced HIV disease was found in male heterosexuals and female people who use drugs (PWID). Heterosexuals (OR 2.11 [95% CI 1.90-2.34]) and PWID (OR 1.55 [95% CI 1.30-1.84]) had a higher risk of late presentation than men who have sex with men (MSM). Blood testing of the blood receivers (OR 1.75 [95% CI 1.36-2.26]) and diagnosed in hospital (OR 1.74 [95% CI 1.65-1.84]) had an increased risk of late presentation compared to those who diagnosis in voluntary counseling and testing (VCT). Heterosexuals (OR 2.86 [95% CI 2.51-3.27]), PWID (OR 2.23 [95% CI 1.83-2.71]), blood testing of the blood receivers (OR 1.58 [95% CI 1.29-1.94]) and diagnosed in hospital (OR 1.85 [95% CI 1.76-1.94]) were also independent risk factors associated with advanced HIV disease. Older age, lower level of education and being divorced or widowed were also associated with late presentation and advanced HIV disease.

conclusionsLate presentation and advanced HIV disease were very common among patients with newly diagnosed HIV in Guangxi, China during 2012-2016. Targeted programs are urgently required to reduce HIV late diagnosis in Guangxi, especially for male heterosexuals, PWID, and patients with characteristics such as older age, lower level of education, divorced or widowed.

Indexed as

Delayed DiagnosisEpidemiological MonitoringAdolescentAdultAge FactorsChinaCounselingCross-Sectional StudiesDrug UsersFemaleHeterosexualityHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedAdvanced HIV diseaseHIV/AIDSLate presentationSouthwestern China

Identifiers

PMID30876476
PMCPMC6420760
OpenAlexW2921629052

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.